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Natural Products
Catalog No. Information
CFN92693 Coelonin

Coelonin shows moderate cytotoxic activity against HepG2 cells.
CFN92694 Neocyclomorusin

Neocyclomorusin displays minimal inhibitory concentration (MIC) value of 4 ug/mL against Klebsiella pneumoniae ATCC11296, Enterobacter cloacae BM47.
CFN92695 Sanggenol A

Sanggenol A shows neuroprotective activity on glutamate-induced cell death in HT22 cells, with EC50 values of 34.03 ± 7.71 uM. Sanggenol A inhibits influenza A viral and pneumococcal neuraminidase (NA), it also disrupts the synergism between influenza A virus and pneumococcal NA in vitro, hence functioning as dual-acting anti-infectives.
CFN90556 Obtusilin

Obtusilin is a impurity from Aglaia odorata Lour.
CFN92696 Butyraxanthone B

Butyraxanthone B exhibits good antiplasmodial activity.
CFN92697 Garcinone E

Garcinone E is active constituents in the anticomplement assay used. Garcinone E exhibits potent activity in vitro against Plasmodium falciparum chloroquine-resistant strain W2, with IC50 values below 3 µM. It has potent cytotoxic effect on all hepatocellular carcinomas cell lines as well as on the other gastric and lung cancer cell lines included in the screen, may be potentially useful for the treatment of certain types of cancer.
CFN92698 Eupatoletin

Reference standards.
CFN92699 (-)-beta-Peltatin

(-)-beta-Peltatin has antimitotic, and antineoplastic activities.
CFN92700 (-)-beta-Peltatin-5-O-beta-D-glucopyranoside

beta-Peltatin-5-O-beta-D-glucopyranoside provides potent cancer cell growth inhibitory activity (GI50 0.1 to <0.03 ug/mL) against a panel of six human cancer cell lines and one murine cancer cell line; it also shows modest antiproliferative activities against the A2780 ovarian cancer cell line, with the IC50 value of 4.9 ± 0.1 uM.
CFN92701 Ophiohayatone C

Standard reference
CFN92702 12-Hydroxyisobakuchiol

Standard reference
CFN92703 3-Hydroxybakuchiol

3-Hydroxybakuchiol exerts cytotoxic and anti-proliferative effects on the TA3/Ha mouse mammary adenocarcinoma cell line and induces a decrease in the mitochondrial transmembrane potential, the activation of caspase-3, the opening of the mitochondrial permeability transport pore (MPTP) and nuclear DNA fragmentation.3-Hydroxybakuchiol has antitumor activity resulting from interactions with the ETC, a system that is already deficient in cancer cells.
CFN92704 Psoracorylifol A

Reference standards.
CFN92705 Pyrochamissanthin

Reference standards.
CFN92706 6-Methoxyluteolin

6-Methoxyluteolin has antioxidant activity, it is a potent inhibitor of histamine release and calcium influx via down-regulation of the FcεRI α chain.
CFN92707 Methyl 4-Hydroxyphenylacetate

Methyl 4-Hydroxyphenylacetate has potent inhibitory activity against tobacco mosaic virus (TMV).
CFN92708 Japonicone D

Standard reference
CFN92709 Qianhucoumarin A

Standard reference
CFN92710 d-Laserpitin

Reference standards.
CFN92711 Ammijin

Standard reference
CFN92712 Marmesin

Marmesin has hepatoprotective potential; it also has cytotoxic with a 50% lethal dose of less than 0.5 micrograms/ml, is not as mutagenic or potentially carcinogenic as are AFB1, imperatorin, or MOP with BL activation.
CFN92713 Gentioflavin

CFN92714 Schizanrin L

Schizanrin L is a natural product from Kadsura coccinea.
CFN92715 Schisantherin C

Schisantherin A, B, C, and D show good effect in lowering the serum glutamic-pyruvic transaminase level of the patients suffering from chronic virus hepatitis.
CFN92716 Gomisin S

Reference standards.
CFN92717 Schineolignin B

Standard reference
CFN92718 Dimethylwulignan A1

Dimethylwulignan A1 is a natural product from Schisandra henryi.
CFN92719 Gomisin F

Standard reference
CFN92720 Ceplignan

(2S,3R)-Ceplignan and (2R,3S)-Ceplignan significantly enhances SERT activity, can used in treatments of neuropsychiatric and digestive disorders.
CFN92721 Kadsulignan L

Kadsulignan L shows in vitro antiviral effects on hepatitis B virus. It also shows moderate platelet-activating factor (PAF) antagonistic activities with the IC50 value of 2.6 x 10(-5) M.
CFN92722 Schisanlignone A

Schisanlignone A and Schisanlignone B show a significant activity against Leukaemia P-388 cell (IG(50) =10 and 40ug/mL, respectively) in vitro.
CFN92723 Schisanlignone C

Schisanlignone C is a natural product from Schisandra henryi.
CFN92724 Schisanlignone D

Schisanlignone D is a natural product from Kadsura japonica.
CFN92725 Kadsulignan N

Standard reference
CFN92726 Heteroclitin C

Heteroclitin C is a natural product from Kadsura heteroclita.
CFN92727 Anwuweizonic acid

Anwuweizonic acid may have inhibitory effects on 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced inflammation in mice. Mixture of coccinic acid and anwuweizonic acid has antifertility activity, shows significant inhibitory activity against human decidual cells and rat luteal cells in vitro.
CFN92728 Kadsurin

Kadsurin has anti-oxidant activity, it induces enzymes capable of scavenging oxygen radical species in the liver. Kadsurin may be valuable antitumor promoters or chemopreventors.
CFN92729 O-Acetylschisantherin L

Reference standards.
CFN92730 Interiotherin C

Interiotherin C may be valuable antitumor promoters or chemopreventors.
CFN92731 O-Methylcedrelopsin

O-Methylcedrelopsin may have vasorelaxing activity.
CFN92732 5-Methoxysuberenone

5-Methoxysuberenone is a natural product from Toddalia asiatica Lam.
CFN92733 Toddaculine

Toddaculine may be beneficial for the prevention and treatment of osteoporosis, it can not only inhibit the differentiation of osteoclasts via activation of the NF-κB, ERK 1/2, and p38 MAPK signaling pathways, but can induce differentiation and mineralization of osteoblasts by regulating differentiation factors. Toddaculine also may serve as a pharmacological prototype for the development of novel anti-leukemic agents, it displays a dual effect as a cell differentiating agent and apoptosis inducer in U-937 cells.
CFN92734 Toddacoumaquinone

Toddacoumaquinone shows a weak activity (EC50 = 10 micrograms/ml) against HSV-1 and HSV-2.
CFN92735 N-Methylflindersine

N-Methylflindersine shows strong toxicity towards brine shrimp larvae, with an LD(50) value of 1.39 microg/ml. It also exhibits potent inhibition against N -formylmethionylleucylphenylalanine-induced superoxide production with IC(50) values less than 12 microM.
CFN92736 Arteminin

Standard reference
CFN92737 Norchelerythrine

Norchelerythrine shows significant inhibitory activity against Staphylococcus aureus ATCC 6538 with MIC values ranging from 12.5 to 50 ug/mL. It exhibits strong antifeeding activity in a concentration-dependant manner with the EC50 of 62.67 ppm.
CFN92738 3-Epidehydropachymic acid

Reference standards.
CFN92739 Polyporenic acid C

Polyporenic acid C shows inhibitory activity against human collagenase. Polyporenic acid C induces apoptosis through the death receptor-mediated apoptotic pathway where the activation of caspase-8 leads to the direct cleavage of execution caspases without the involvement of the mitochondria.
CFN92740 Dehydroeburicoic acid

Dehydroeburicoic acid induces necrotic cell death that involves Ca(2+) overload, mitochondrial dysfunction, and calpain activation in human glioblastomas. Dehydroeburicoic acid and Eburicoic acid have antioxidant and anti-inflammatory activities by the decrease of inflammatory cytokines and an increase of antioxidant enzyme activity, can protect the liver from CCl4-induced hepatic damage.
CFN92741 6alpha-Hydroxypolyporenic acid C

6alpha-Hydroxypolyporenic acid C is a natural product from Wolfiporia cocos (Schw.) Ryv.