Natural Products
| Catalog No. | Information |
| CFN92833 | 3-Deoxysappanchalcone 3-Deoxysappanchalcone is an effective HO-1 inducer at the translational level. 3-Deoxysappanchalcone has anti-inflammatory, and anti-influenza virus activities, the mechanism involved anti-apoptosis and anti-inflammation activities in vitro. It has inhibitory activity on MMP-9 expression and production in TNF-α-treated cells, is mediated by the suppression of AP-1 and NF-κB activation. |
| CFN90601 | Daurinoline Daurinoline is a non-competitive antagonist, it exerts marked relaxation effect on basilar artery of rabbits through non-competitive antagonism, it would have a protective function on microcirculation of cerebral pia mater, which may be beneficial to relieve cerebral ischemic injury. Daurinoline could significantly reverse noradrenaline induced constriction of pial arterioles and venules, and increase the number of blood vessels which were decreased by noradrenaline. |
| CFN92834 | (2R)-8-Methylsocotrin-4'-ol Reference standards. |
| CFN92835 | Eriosemation Eriosemation significant androgen receptor (AR) inhibition activity, suggests that it could be a promising candidate for further evaluation for prostate cancer prevention or management. |
| CFN92836 | Peroxydehydrotumulosic acid 5alpha,8alpha-Peroxydehydrotumulosic acid exhibits inhibitory effects against the Epstein-Barr virus early antigen (EBV-EA) activation induced by 12-O-tetradecanoylphorbol-13-acetate (TPA) in Raji cells. |
| CFN92837 | Dehydrotumulosic acid Dehydrotumulosic acid shows anti-inflammatory activity. |
| CFN92838 | Poricoic acid A(F) Poricoic acid A(F) shows anti-inflammatory activity. It is a potential whitening active ingredient, it exhibits good inhibitory effects on the activities of monophenolase and diphenolase in mushroom tyrosinase, as well as a certain inhibitory effect on tyrosinase in B16 cells. |
| CFN90599 | Lirioprolioside B Lirioprolioside B is a natural product from Liriope spicata (Thunb.) Lour. |
| CFN92839 | Lemannine Standard reference |
| CFN92840 | (+)-Sophoranol (+)-Sophoranol exhibits antiviral activity against the Coxsackie virus B3. It also shows potent anti-HBV activity with an inhibitory potency against HBsAg secretion and against HBeAg secretion. |
| CFN92841 | Schisandrin C epoxide Reference standards. |
| CFN92842 | Heteroclitin B Standard reference |
| CFN92843 | Corynantheine Corynantheine shows pronounced activity against Leishmania major promastigotes (IC50 at the micromolar level) but no significant in vitro antiplasmodial activity (against chloroquinesensitive Plasmodium falciparum). |
| CFN92844 | Dihydrocorynantheine Dihydrocorynantheine shows pronounced activity against Leishmania major promastigotes (IC50 at the micromolar level) but no significant in vitro antiplasmodial activity (against chloroquinesensitive Plasmodium falciparum). Dihydrocorynantheine exhibits significant vasodilating activity against phenylephrine-induced contraction in rat thoracic aorta rings (IC(50) = 6.73 μg/mL), it also shows weak inhibitory action on KCl-induced contraction. |
| CFN92845 | (Z)-23-Coumaroylhederagenin (Z)-23-Coumaroylhederagenin shows significant cytotoxicity against two human tumor cell lines, namely, oral epidermoid carcinoma KB and colorectal carcinoma HT29, and the IC(50) value in the range 1.2-3.6 microM. |
| CFN92846 | Brachynoside Brachynoside is a natural product from Clerodendrum japonicum. |
| CFN92847 | Lamalbid Standard reference |
| CFN92848 | Cardanol (C15:1) Cardanol (C15:1) possesses the same side chain as anacardic acid (C15:1), acted neither as a substrate nor as an inhibitor of lipoxygenase-1. |
| CFN92849 | Pelandjauic acid Pelandjauic acid is a natural product from Scutellinia ascoboloides. |
| CFN92850 | Mesembrenone Mesembrenone, sucrose and obtusalin, the extracts of Sceletium tortuosum show antimalarial activity with activity values ranging between 1.47 ug/ml and 7.32 ug/ml, well below the 10 ug/ml cut off value. |
| CFN92851 | Danshinspiroketallactone Reference standards. |
| CFN92852 | Nirtetralin Nirtetralin suppresses effectively both HBsAg and HBeAg expression. |
| CFN92853 | Gnetumontanin B Gnetumontanin B shows potent inhibition of TNF-alpha. |
| CFN92854 | Viniferin α-Viniferin has anti-oxidant and anticancer activities, it strongly inhibits the activities of the two CYPs dose dependently. α-Viniferin suppresses the expression of proinflammatory genes iNOS and COX-2 in the early stage of inflammation by inhibiting the Akt/PI3K-dependent NF-κB activation and inhibits the production of proinflammatory mediators NO and PGE2 in the late stage by stimulating Nrf2-mediated HO-1 signaling pathway in LPS-stimulated BV2 microglial cells. ɛ-Viniferin and vincristine can enhance the anti-tumor effects efficiently by inducing HepG2 cell apoptosis. |
| CFN92855 | 4',7-Dihydroxyflavone 4',7-Dihydroxyflavone can induce transcription of nodulation (nod) genes in Rhizobium meliloti. It has inhibitory activities against COX-2. |
| CFN92856 | Tecomin Tecomin is a potential bioactive compound from the flowers of Trollius chinensis, it was easily absorbed and rapidly metabolized into veratric acid in vivo , and then the latter was eliminated slowly. |
| CFN92857 | 3,5-Dimethoxybenzylalcohol 3,5-Dimethoxybenzylalcohol is a natural product from Pinus sylvestris. |
| CFN92858 | Loureirin C Loureirin C can inhibit the activities of thrombin in vitro effectively. |
| CFN92859 | Coronaridine Coronaridine is an antitumor agent. Coronaridine congeners inhibit hα3β4 AChRs by blocking the ion channel's lumen and probably by additional negative allosteric mechanisms by interacting with a series of non-luminal sites. |
| CFN92860 | (-)-Bicuculline methochloride (-)-Bicuculline methochloride is a GABAA-receptor antagonist. Exposure to 100 microM (-)-Bicuculline methochloride for 48 hr can result in prominent CA1 cell death. |
| CFN92861 | Kansuiphorin C Kansuiphorin C shows cytotoxic activity. |
| CFN92862 | 3-O-(2'E ,4'Z-decadienoyl)-20-deoxyingenol 3-O-(2'E ,4'Z-decadienoyl)-20-deoxyingenol, one toxic terpenoid from raw Gansui. It has strong cytotoxicity against human normal cell lines L-O2 and GES-1 with dose-dependent relationships. |
| CFN92863 | Kansuinine A Kansuinine A possesses analgesic props, it also shows NGF inducing activity. |
| CFN92864 | 3-O-(2'E ,4'Z-decadienoyl)-20-O-acetylingenol 3-O-(2′E,4′Z-decadienoyl)-20-O-acetylingenol, one toxic terpenoid from raw Gansui. It has strong cytotoxicity against human normal cell lines L-O2 and GES-1 with dose-dependent relationships . It shows antinematodal activity against the nematode, Bursaphelenchus xylophilus, at a minimum effective dose (MED) of 5 microg/cotton ball. 3-O-(2'E,4'Z-decadienoyl)-20-O-acetylingenol induces the cytotoxicity of intestinal epithelial cells of rats (IEC-6 cells) depends on induction of cell apoptosis via mitochondrial pathway and cell cycle arrest.3-O-(2'E,4'Z-decadienoyl)-20-O-acetylingenol, kansuinine B and kansuinine A can markedly promote SPL proliferation and NO production by PMphi at concentrations from 0.78 to 12.50 microg/mL, hence the they are believed to be important proinflammatory components of the roots of E. kansui. |
| CFN92865 | 3-O-(2'E ,4'E-decadienoyl)-20-O-acetylingenol 3-O-(2′E,4′E-decadienoyl)-20-O-acetylingenol has strong cytotoxicity against human normal cell lines L-O2 and GES-1 with dose-dependent relationships. |
| CFN92866 | Kansuinine B Kansuinine B shows cytotoxic ,and analgesic activities, treatment with kansuinine B and kansuinine A represents a novel method to block the IL-6-induced effects. |
| CFN92867 | 3-O-(2'E,4'Z-Decadienoyl)ingenol Kansuiphorin C and 3-O-(2′E,4′Z-decadienoyl)-ingenol exhibit significant anticomplement activity with respective 50% inhibitory concentration values of 44.1±3.8 and 89.5±5.5 uM. 20-O-acetyl-[3-O-(2'E,4'Z)-decadienoyl]-ingenol and 3-O-(2'E,4'Z)-decadienoylingenol show the same antinematodal activity against the nematode, Bursaphelenchus xylophilus, at a minimum effective dose (MED) of 5 microg/cotton ball. |
| CFN92868 | 3-O-(2'E,4'E-Decadienoyl)ingenol 3-O-(2'E,4'E-Decadienoyl)ingenol , one toxic terpenoid from raw Gansui.3-O-(2′E,4′E-decadienoyl)-ingenol and 3-O-(2′E,4′Z-decadienoyl)-20-O-acetyl-ingenol show cytotoxicity on Namalwa cells with IC 50 values of 7.6 and 5.2 umol·L-1, respectively. |
| CFN92869 | Kansuinine E Reference standards. |
| CFN92870 | 20-Deoxyingenol Standard reference |
| CFN92871 | Jolkinolide A Jolkinolide A has anti-tumor activity. It inhibited VEGF expression in A549 cells through the inhibition of the Akt-STAT3-mTOR signaling pathway, and directly inhibited the proliferation and migration of HUVECs. |
| CFN92872 | Jolkinolide E Standard reference |
| CFN92873 | Ebracteolatanolide A Standard reference |
| CFN92874 | Yuexiandajisu D Yuexiandajisu D is slightly active against ANA-1 cells with an IC50 value 2.88 x 10(-1)microM. It shows moderate cytotoxic activity against cancer cell lines on HCT-8 and Bel-7402, with IC50 values of 2.66 and 3.76 microM, respectively. |
| CFN92875 | Yuexiandajisu E Standard reference |
| CFN92876 | Hugorosenone Hugorosenone has antifungal activity. It also exhibits activity against Anopheles gambiae mosquito larvae. |
| CFN92877 | Didemethylpseudoaspidin AA Didemethylpseudoaspidin AA is a natural product from Euphorbia ebracteolata. |
| CFN92878 | Jolkinol A Jolkinol A can inhibit both MCF-7 (breast adenocarcinoma), NCI-H460 (non-small cell lung cancer) cell lines, with GI50 values ranging between 40.9 microM and 95.3 microM. |
| CFN92879 | Fischeria A Standard reference |
| CFN92880 | 2,4-Dihydroxy-6-methoxy-3-formylacetophenone 2,4-Dihydroxy-6-methoxy-3-formylacetophenone is a natural product from Euphorbia pekinensis Rupr. |
