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Natural Products
Catalog No. Information
CFN92557 9,10-Anthracenedione

9,10-Anthracenedione is a natural product from Rubia cordifolia L.
CFN92558 1,2-dihydroxy-3-methyl-anthracene-9,10-dione

Reference standards.
CFN92559 (+)-Pteryxin

(+)-Pteryxin has muscle-relaxant props, it also shows hepatoprotective and nitric oxide prodn. inhibitory activity.
CFN92560 Peucedanocoumarin III

Peucedanocoumarin Ⅲ can induce rice resistance to blast disease.
CFN92561 Chikusetsusaponin V methyl ester

Standard reference
CFN92562 Momordin II

Highly purified Momordin II inhibits cell-free protein synthesis, releases adenine from rat liver ribosomes and from DNA, and has no RNase activity.
CFN92563 Momordin IIa

Momordin IIa is a natural product from Momordica cochinchinensis.
CFN92564 Methyl salvionolate A

Methyl salvionolate A has anti-HIV-1 activity.
CFN92565 Isosalvianolic acid C

Isosalvianolic acid C exhibits more potent activity than probucol except for salvianolic acid F .
CFN92566 Purpurin

Purpurin is one of the natural colorants extracted from madder roots and other Rubiaceae family plants. Purpurin is a novel specific inhibitor of Adipocyte-derived leucine aminopeptidase, it exhibits anti-angiogenic, antifungal, antibiotic, and antioxidative activities.
CFN92567 1-Hydroxy-2-methylanthraquinone

1-Hydroxy-2-methylanthraquinone exhibits promising larvicidal activity.
CFN90506 Tetrahydroberberine

Tetrahydroberberine, with D(2) receptor antagonist and 5-HT(1A) receptor agonist properties, has significant potential as a therapeutic for treatment of FD; it has antidopaminergic effect, and other pharmacological action on the central nervous system. Tetrahydroberberine can inhibit the rabbit platelet aggregation.
CFN90507 Tetrahydroepiberberine

Tetrahydroepiberberine is a natural product from Sinomenium acutum.
CFN90508 Oxoglaucine

Oxoglaucine exerts immunomodulatory effect in vivo in a dose-dependent and protocol-dependent manner, it also exhibits significant antiplatelet aggregation activity against rabbit platelets induced by thrombin, arachidonic acid, collagen or platelet activating factor. Oxoglaucine and pachypodol are anti-picornavirus compounds, phosphatidylinositol 4-kinase III beta (PI4KB) as the direct target of them.
CFN90509 Berberrubine

Berberrubine possesses diverse pharmacological activities, including glucose-lowering, lipid-lowering, anti-inflammatory, and anti-tumor effects. Berberrubine dose-dependently inhibits IL-8 and MCP-1 protein levels in the media and mRNA expression of the cells stimulated with IL-1beta or TNF-alpha.
CFN90510 Columbianetin acetate

Columbianetin may be helpful in regulating mast cell-mediated allergic inflammatory responses, the absorption of columbianetin acetate is a passive diffusion process without pH-dependent.
CFN92568 Alizarin

Alizarin has a selective and effective inhibitory activity towards cancerous cells, it acts through the inhibition of ERK phosphorylation and cell cycle arrest in the S-phase. Alizarin has antigenotoxic activity, which can be explained by inhibition of CYP activities responsible for activating the mutagens.
CFN92569 Alizarin 2-methyl ether

Alizarin 2-methyl ether enhances adipocyte differentiation by up to 131%, it could be beneficial in the treatment of diabetes.
CFN92570 Tectoquinone

Tectoquinone exhibits strong mosquito larvicidal activity.
CFN92571 Triptotin F

Standard reference
CFN92572 Charantadiol A

Charantadiol A is a natural product from Momordica charantia.
CFN92573 3-O-Caffeoylquinic acid methyl ester

3-O-Caffeoylquinic acid methyl ester is a natural product from Morus alba L.
CFN90511 Phillygenin

Phillyrin, (+)-Phillygenin, and (-)-phillygenin exert the strongest inhibitory activities on NO production with IC(50) values.
CFN90512 10-Hydroxy-2-decenoic acid

10-Hydroxy-2-decenoic acid is a potential HDACI which inhibits the proliferation of FLS cells by PI3K-AKT pathway; it exerts an inhibitory effect on VEGF-induced angiogenesis, partly by inhibiting both cell proliferation and migration. 10-Hydroxy-2-decenoic acid activates AMPK, and insulin independently enhances glucose uptake following translocation of Glut4 to PM; it also can prevent UVA-induced damage and inhibit MMP-1 and MMP-3 expressions.
CFN90513 Periplocin

Periplocin has anti-cancer, and potent immunoregulatory effects, it induces apoptosis and inhibits growth of cancer cells by the beta-catenin/Tcf signaling pathway. Periplocin is used for treatment of rheumatoid arthritis, reinforcement of bones and tendons, palpitations or shortness of breath and lower extremity edema in traditional medicine.
CFN90514 Periplogenin

Periplogenin plays protective roles against thyrotoxicosis and associated cardiovascular problems, are mediated through its direct antithyroidal and/or LPO inhibiting properties. Periplogenin induces necroptotic cell death through oxidative stress in HaCaT cells and ameliorates skin lesions in the TPA- and IMQ-induced psoriasis-like mouse models.
CFN90515 2-Bromo-1-(3-thienyl)-1-ethanone

Reference standards.
CFN90516 Aristolochic acid C

Aristolochic acid C could as the larval feeding stimulants.
CFN90517 7-Hydroxyaristolochic acid A

7-Hydroxyaristolochic acid A is a natural product from Aristolochia debilis Sieb. et Zucc.
CFN90518 Deoxyandrographolide

Deoxyandrographolide promotes glucose uptake through glucose transporter-4 translocation to plasma membrane in L6 myotubes and exerts antihyperglycemic effect in vivo.
CFN90519 Amarogentin

Amarogentin incorporated in liposomes or niosomes may have clinical application in the treatment of leishmaniasis. It plays cemopreventive/therapeutic role during liver carcinogenesis through modulation of cell cycle and apoptosis. Amarogentin may offer therapeutic potential for preventing or treating thromboembolic disorders, it prevents platelet activation through the inhibition of PLC γ2-PKC cascade and MAPK pathway.
CFN90520 (+)-Corlumidine

Reference standards.
CFN90521 Demethylwedelolactone

Demethylwedelolactone has trypsin inhibitory effect, it exerts anti-invasive growth effect on breast cancer cells.
CFN90522 Rhapontisterone B

Reference standards.
CFN90523 Acetylshikonin

Acetylshikonin has anti-cancer and anti-inflammatory activity, it is a novel general P450 inhibitor with IC50 values of 1.4-4.0 μM for all tested P450s. Acetylshikonin exhibits weak cytotoxicity against human umbilical vein endothelial cells (HUVECs) with IC50 of over 20 microM, exhibits the antiangiogenic and antitumorigenic effects by suppressing proliferation and angiogenic factors. Certain shikonin derivatives(such as Acetylshikonin) act as modulators of the Nur77-mediated apoptotic pathway.
CFN90524 Anemonine

Anemonin, a naturally occurring selective iNOS inhibitor, it has potential anti-inflammatory effect; it is also a potent protective molecule for osteoarthritis, it delays osteoarthritis progression by suppressing ECM loss and chondrocyte hypertrophy partially by suppressing IL-1β/NF-κB pathway activation. Anemonin can alleviate nerve injury after cerebral ischemia and reperfusion (i/r) in rats by improving antioxidant activities and inhibiting apoptosis pathway. Anemonin inhibits melanin synthesis by inhibiting the transcription of the genes encoding MITF, TYR, TRP1, and TRP2.
CFN90525 Baldrinal

Baldrinal, valtrate, and acevaltrate are the quality control compounds of Valeriana jatamansi Jones. Baldrinal shows selective cytotoxicity against metastatic prostate cancer (PC-3M) and colon cancer (HCT-8) cell lines.
CFN90526 Cistanoside A

Cistanoside A possesses protective activities on CCl4 induced hepatotoxicity in mice, which is involved with increasing free radicals clearing activities, alleviating lipid-overoxidation damage, and improving respiratory chain function in mitochondria.
CFN90527 Corydine

Corydine is the adrenolytic and weak cholinergic agent, it shows antimicrobial, and antineoplastic activities. Corydine shows irritant and respiratory stimulant and CNS depressant activities. Injected intravenously in rabbits corydine produced an initial fall in blood pressure followed by a return to normal or above normal.
CFN90528 Corytuberine

Corytuberine was inhibited only by naloxone and that of bulbocapnine preferentially by yohimbine.
CFN90529 3-O-Acetyl-alpha-boswellic acid

3-O-Acetyl-alpha-boswellic acid has strong anti-inflammatory activity.
CFN90530 3-O-Acetyl-beta-boswellic acid

3-O-Acetyl-beta-boswellic acid has antitumor activity, it inhibits synthesis of DNA, RNA and protein in human leukemia HL-60 cells in a dose dependent manner with IC50 values ranging from 0.6 to 7.1 microM.
CFN90531 3-O-Acetyl-11-keto-beta-boswellic acid

3-O-Acetyl-11-keto-beta-boswellic acid inhibits 5-lipoxygenase product formation with an IC(50) of 1.5 m muM.
CFN90532 (-)-Curine

(-)-Curine can inhibit viability of hepatocellular carcinoma cells in regardless of p53 status.
CFN90533 Negsehisandrin G

Reference standards.
CFN90534 Daurisoline

Daurisoline is a hERG inhibitor and also an autophagy blocker.Daurisoline has antiarrhythmic effects, it( at concentrations below 30 uM) exerts a blocking effect on hERG, but does not affect the expression and function of the hERG channel, it also can inhibit early afterdepolarizations (EADs) which may be associated with its blockade effects on I(Ca-L). Daurisoline and its isomers show cytoprotective effects on ischemic injury in cultured pheochromocytoma (PC12) cells, which are mediated by blocking Ca2+ influx into cells.
CFN90535 Cucurbitacin S

Cucurbitacins from Wilbrandia ebracteata have analgesic effects. Cucurbitacin S has anticancer and antiinflammatory activities.
CFN90536 Dihydrokavain

Dihydrokavain may play an important role in regulation of GABAergic neurotransmission, it non-competitively inhibits the specific binding of [3H]-batrachotoxinin-A 20-alpha-benzoate to receptor site 2 of voltage-gated Na+ channels. Dihydrokavain may treat sleep disturbances, as well as stress and anxiety.
CFN90537 Embelin

Embelin is an inhibitor of X-linked inhibitor of apoptosis (XIAP) with IC50 of 4.1 μM in a cell-free assay.Embelin has antitumor, antioxidant and anti-inflammatory activities. Embelin can enhance TRAIL-induced cell apoptosis through DR4 and DR5 upregulation and decrease IL-6-induced STAT3 phosphorylation, that combination of low-toxicity Embelin and TRAIL may become as a potential antileukemia strategy.
CFN90538 Gymnemic acid I

Gymnemic acid I is a protein biosynthesis inhibitor, it as antisweet principles.