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Natural Products
Schizonepeta tenuifolia

Schizonepeta tenuifolia (ST) is a well-known herb to treat the cold and its associated headache. However, the anti-inflammatory mechanism of ST in mouse peritoneal macrophages is not clear. In study, It demonstrated that ST inhibited lipopolysaccaride (LPS)-induced tumor necrosis factor (TNF)-alpha and interleukin (IL)-6 production. The maximal inhibition rate of TNF-alpha and IL-6 production by ST (2 mg/ml) was 48.01 +/- 2.8% and 56.45 +/- 2.8%, respectively. During the inflammatory process, cyclooxygenase (COX)-2 and inducible nitric oxide synthase (iNOS) were increased in mouse peritoneal macrophages. However, treated with ST decreased the protein level of COX-2 and iNOS, as well as the production of PGE(2) and NO in LPS-stimulated mouse peritoneal macrophages. In addition, ST inhibited the phosphorylation of MAPK.
Schizonepeta tenuifolia  has been used for the treatment of skin disorders, allergic dermatitis, eczema, and inflammatory diseases.

Schizonepeta tenuifolia
Research products of Schizonepeta tenuifolia
Catalog Product Name CAS Number Manual
CFN98800Oleanolic acid508-02-1  PDF
CFN97259Ursolic acid77-52-1  PDF
CFN98713Daucosterol474-58-8  PDF
CFN99916Beta-Sitosterol83-46-5  PDF
CFN98784Luteolin491-70-3  PDF
CFN98843Apigenin520-36-5  PDF
CFN98839Hesperidin520-26-3  PDF
CFN98405Hesperetin 7-O-glucoside31712-49-9  PDF
CFN92764Tilianin4291-60-5  PDF
CFN99453Cinnamic acid140-10-3  PDF
CFN98565Luteolin-7-O-glucoside5373-11-5  PDF
CFN98512Luteolin-7-O-glucuronide29741-10-4  PDF
CFN99100Succinic acid110-15-6  PDF
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