Scutellaria barbata is a plant used in traditional Chinese medicine. Other names include ban zhi lian, scullcap or skullcap, barbat skullcap, skute barbata, or herba scutellariae barbatae.
Scutellaria barbata is used in some traditional herbal sleeping remedies and for anxiety, migraines, and depression. Bionovo is testing its use as a treatment for advanced breast cancer and pancreatic cancer.
Three new neo-clerodane diterpenoids, named scutelinquanines A–C (1–3), were isolated from the whole plant of Scutellaria barbata. Their structures were established on the basis of detailed spectroscopic analyses. In vitro, the isolated three new compounds showed significant cytotoxic activities against three human cancer lines (HONE-1 nasopharyngeal, KB oral epidermoid carcinoma, and HT29 colorectal carcinoma cells), and gave IC50 values in the range 2.7–6.7 μM.
Scutellaria barbata D.Don
Research products of Scutellaria barbata D.Don
Screening Libraries
Sophora flavescens Ait
A unique collection of 38 natural compounds from Sophora flavescens Ait
A unique collection of 38 natural compounds from Sophora flavescens Ait
Glycyrrhiza glabra L.
A unique collection of 22 natural compounds from Glycyrrhiza glabra L.
A unique collection of 22 natural compounds from Glycyrrhiza glabra L.
Pteris semipinnata L.
A unique collection of 24 natural compounds from Pteris semipinnata L.
A unique collection of 24 natural compounds from Pteris semipinnata L.
Lycium chinense
A unique collection of 37 natural compounds from Lycium chinense
A unique collection of 37 natural compounds from Lycium chinense
Epimedium brevicornum Maxim
A unique collection of 25 natural compounds from Epimedium brevicornum Maxim
A unique collection of 25 natural compounds from Epimedium brevicornum Maxim
Morus alba L
A unique collection of 55 natural compounds from Morus alba L
A unique collection of 55 natural compounds from Morus alba L
Glehnia littoralis
A unique collection of 25 natural compounds from Glehnia littoralis
A unique collection of 25 natural compounds from Glehnia littoralis
Eucalyptus robusta Smith
A unique collection of 27 natural compounds from Eucalyptus robusta Smith
A unique collection of 27 natural compounds from Eucalyptus robusta Smith
Phellodendron Chinense Schneid.
A unique collection of 22 natural compounds from Phellodendron Chinense Schneid.
A unique collection of 22 natural compounds from Phellodendron Chinense Schneid.