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|Size /Price /Stock
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More articles cited ChemFaces products.
Natural Product Res.&Deve....2022...Plant Sci.2021, 313:111069.J Sep Sci.2020, 43(22):4148-4161.Nat Prod Sci.2018, 24(3):206J Nat Prod.2019, 82(4):1002-1008Nutraceuticals2022, 2(3),150-161Anal Bioanal Chem....2018...Biochem Biophys Res Commun....2017...
Sci Rep.2021, 11(1):14180. Indian J Pharm Sci.2022, 84(3):144-151Mol Immunol. 2016, 78:121-132Phytomedicine.2022, 110:154597.Inflammation2015, 38(1):445-55Sci Rep. 2017, 12953(7)Sci Rep.2019, 9(1):6429Phytochemistry Letters2021, 43:80-87.
J of l. Chroma.&Related Tech...2020...Molecules.2020 ,25(16):3697.Environ Toxicol.2019, 34(12):1354-1362J Biochem Mol Toxicol.2017, 31(9)Research Square2021, 10.21203.J Pharm Anal.2016, 6(6):363-373Int J Mol Sci.2022, 23(10):5813.
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Drug Des Devel Ther.2020, 14:5189-5204.Biomol Ther (Seoul).2023, 31(1):40-47.J. Traditional Thai Medical Res. 2022,8(1):1-14.J Pharmaceut Biomed2020, 182:113110BMC Complement Altern Med.2018, 18(1):221J AOAC Int.2021, 104(6):1634-1651.J Adv Res.2021, 35:245-257. Exp Parasitol.2017, 183:160-166International Food Research Journal2018, 25(6):2560-2571J Pain Res.2022, 15:3469-3478.
Related Screening Libraries
||(+)-9'-O-trans-feruloyl-5,5'-dimethoxylariciresinol may have anti-allergic inflammatory effect, it can inhibit release of histamine from mast cells. It shows cytotoxicity against a small panel of human tumor cell lines, with ED50 values of 9.86 to approximately 12.68 microg/ml.|
||TNF-α | IL Receptor|
|Arch. Pharm. Res.,2014 Apr;37(4):467-72. |
|A new neolignan and lignans from the stems of Lindera obtusiloba Blume and their anti-allergic inflammatory effects.[Pubmed: 24014307 ]|
METHODS AND RESULTS:
A new neolignan, linderin A (1), together with six known lignans, (+)-xanthoxyol (2), pluviatilol (3), actiforin (4), (+)-syringaresinol (5), (+)-(7S,8R,8'R)-acuminatolide (6), and (+)-9'-O-trans-feruloyl-5,5'-dimethoxylariciresinol (9-O-Feruloyl-5,5'-dimethoxylariciresinol,7) were isolated from the stems of Lindera obtusiloba Blume (Lauraceae). Their chemical structures were elucidated by a combination of spectroscopic analysis and chemical reaction, and the absolute configuration of 1 was determined by Mosher's esterification. The effect of compounds 1-7 on tumor necrosis factor (TNF)-α, interleukin(IL)-6, and their inhibitory activity of histamine release were examined using human mast cells. Among the lignans tested, compounds 1, 3, 4, 6, and 7 inhibited release of histamine from mast cells. Especially, compounds 1 and 4 suppressed the gene expressions of pro-inflammatory cytokines, TNF-α, and IL-6 in human mast cells.
Our findings suggest that the lignan constituents in L. obtusiloba may contribute to its anti-allergic inflammatory effects.
||The herbs of Viburnum cylindricum
||Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
||Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
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||The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.IF=36.216(2019)PMID: 29328914
Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.IF=22.415(2019)PMID: 32004475
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.IF=14.548(2019)PMID: 29149595
ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.IF=13.903(2019)PMID: 29553709
Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.IF=13.297(2019)PMID: 28005066
Sci Adv. 2018 Oct 24;4(10): eaat6994. doi: 10.1126/sciadv.aat6994.IF=12.804(2019)PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
|Arch Pharm Res. 1999 Aug;22(4):417-22. |
|Two new lignans from Lindera obtusiloba blume.[Pubmed: 10489885]|
METHODS AND RESULTS:
Two new furanolignans (3, 5), together with three known lignans (1, 2, 4), were isolated from the stem of Lindera obtusiloba (Lauraceae). The structures of the compounds were determined as actifolin (1), pluviatilol (2), 5,6-dihydroxymatairesinol (3), (+)-syringaresinol (4), and (+)-9'-O-trans-feruloyl-5,5'-dimethoxylariciresinol (9-O-Feruloyl-5,5'-dimethoxylariciresinol,5) on the basis of physicochemical and spectroscopic evidences.
Compounds 1, 2, 3, and 5 showed cytotoxicity against a small panel of human tumor cell lines with ED50 values of 3.40 to approximately 19.27 microg/ml.
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