Anemosapogenin | CAS:85999-40-2 | Manufacturer ChemFaces

Anemosapogenin

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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.

Size /Price /Stock	10 mM * 1 mL in DMSO / $49.9 / In-stock
Other Packaging	*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap

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Description:

Anemosapogenin shows potent anti-tumor effect in vivo, but it has some toxicity, structure modification should be needed.

In vivo:

Chinese Journal of Hospital Pharmacy, 2003 , 23 (9) :532-3.

The anti-tumor effect of the extract from Radix Pulsatillae[Reference: WebLink]

To extract Anemosapogenin from Radix Pulsatillae and study its anti tumor activity.
METHODS AND RESULTS:
Total saponins were isolated from Radix Pulsatillae , then hydrolyze into sapogenins , the sapogenins were purified by column chromatography. The furified substance was mixed with vegetable oil as suspension of different concentrations. Mice with transplantable tumors(HepA liver carcinoma, Ehrlich ascites cancer)were administrated continuously for ten days by i.p. with different dosages according to the mice weight. The anti tumor effect in vivo and the rate of life elongation of the mice was observed. Low concentration group and middle concentration group had obvious effect on inhibiting the growth of HepA liver carcinoma in vivo, but the high concentration group had little effect . However, the life elongation effect was not obvious.
CONCLUSIONS:
The extract from Radix Pulsatillael (3b,23 dihydroxyl 20(29) lupene 28 acid)shows potent anti-tumor effect in vivo, but it has some toxicity, structure modification should be needed.

Anemosapogenin Description

Source:	The branches of Platanus acerifolia
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Product Name	Anemosapogenin
Price:	$138 / 20mg
CAS No.:	85999-40-2
Catalog No.:	CFN90310
Molecular Formula:	C₃₀H₄₈O₄
Molecular Weight:	472.71 g/mol
Purity:	>=98%
Type of Compound:	Triterpenoids
Physical Desc.:	White cryst.
Source:	The branches of Platanus acerifolia
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS SDF
Similar structural:	Comparison (Web) (SDF)
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Anticancer Compound Library Triterpenoids Compound Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	2.1155 mL	10.5773 mL	21.1546 mL	42.3092 mL	52.8865 mL
5 mM	0.4231 mL	2.1155 mL	4.2309 mL	8.4618 mL	10.5773 mL
10 mM	0.2115 mL	1.0577 mL	2.1155 mL	4.2309 mL	5.2887 mL
50 mM	0.0423 mL	0.2115 mL	0.4231 mL	0.8462 mL	1.0577 mL
100 mM	0.0212 mL	0.1058 mL	0.2115 mL	0.4231 mL	0.5289 mL

CFN90772	Cussosaponin C	366814-42-8	1204	C₅₉H₉₆O₂₅
CFN98682	Betulonic acid	4481-62-3	454.7	C₃₀H₄₆O₃
CFN97504	20-Hydroxy-3-oxo-28-lupanoic acid	93372-87-3	472.7	C₃₀H₄₈O₄
CFN99896	Alphitolic acid	19533-92-7	472.7	C₃₀H₄₈O₄
CFN92092	2alpha-hydroxy-3beta-acetyloxy-betulic acid	1163728-89-9	514.8	C₃₂H₅₀O₅
CFN98305	3,27-Dihydroxy-20(29)-lupen-28-oic acid methyl ester	263844-79-7	486.7	C₃₁H₅₀O₄
CFN98306	3-Acetoxy-27-hydroxy-20(29)-lupen-28-oic acid methyl ester	263844-80-0	528.8	C₃₃H₅₂O₅
CFN90310	Anemosapogenin	85999-40-2	472.71	C₃₀H₄₈O₄
CFN90182	Anemoside A3	129724-84-1	750.96	C₄₁H₆₆O₁₂
CFN80453	Pulsatilla saponin D	848784-85-0	913.10	C₄₇H₇₆O₁₇