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    Natural Products
    Momordicoside K
    Momordicoside K
    Information
    CAS No. 81348-84-7 Price
    Catalog No.CFN92305Purity>=98%
    Molecular Weight648.9Type of CompoundTriterpenoids
    FormulaC37H60O9Physical DescriptionPowder
    Download Manual    COA    MSDS    SDFSimilar structuralComparison (Web)  (SDF)
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    * Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
    According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
    Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
    Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
    Our products had been exported to the following research institutions and universities, And still growing.
  • Weizmann Institute of Science (Israel)
  • Calcutta University (India)
  • University of Perugia (Italy)
  • Leibniz Institute of Plant Bioc... (Germany)
  • Funda??o Universit├íria de Dese... (Brazil)
  • Univerzita Karlova v Praze (Czech Republic)
  • The Vancouver Prostate Centre (... (Canada)
  • Martin Luther University of Hal... (Germany)
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  • Package
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  • Biological Activity
    Description: Momordicoside K has antidiabetic activity.
    In vitro:
    Nat Prod Commun. 2014 Jun;9(6):765-9.
    Novel cucurbitane triterpenoids and anti-cholinesterase activities of constituents from Momordica charantia L.[Pubmed: 25115074]

    METHODS AND RESULTS:
    The C-19 epimers of 5beta,19-epoxycucurbita-6,23(E),25(26)-triene-3f,19-diol (1) and 5/,19-epoxy-25-methoxycucurbita-6,23-diene-3beta,19-diol (2) along with (19R,23E)-5beta,19-epoxy-19-methoxycucurbita-6,23,25-trien-3beta-ol (3), (23E)-5beta,19-epoxycucurbita-6,23-diene-3beta,25-diol (4), ligballinol (5), charantin (6) and Momordicoside K(7) were isolated from the green fruits of Momordica charantia. The (S)-epimers of 1 and 2 are the first reports in nature.
    CONCLUSIONS:
    The acetyl- and butyryl-cholinesterase inhibitory activities of the isolated compounds were evaluated, and 5 showed the highest activity of these compounds against butyrylcholinesterase (IC50 = 32.20 microM) with a reversible and non-competitive inhibition mode.
    Momordicoside K Description
    Source: The herbs of Mormodica charantia L.
    Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 1.5411 mL 7.7053 mL 15.4107 mL 30.8214 mL 38.5267 mL
    5 mM 0.3082 mL 1.5411 mL 3.0821 mL 6.1643 mL 7.7053 mL
    10 mM 0.1541 mL 0.7705 mL 1.5411 mL 3.0821 mL 3.8527 mL
    50 mM 0.0308 mL 0.1541 mL 0.3082 mL 0.6164 mL 0.7705 mL
    100 mM 0.0154 mL 0.0771 mL 0.1541 mL 0.3082 mL 0.3853 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.