Europine N-oxide | CAS:65582-53-8 | Manufacturer ChemFaces

Europine N-oxide

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Size /Price /Stock	10 mM * 1 mL in DMSO / Inquiry
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Description:

Supinine, lasiocarpine-N-oxide and Europine N-oxide exhibit virucidal activity to Poliomyelitis, Coxsackie, Semliki forest, Vesicular stomatitis and Herpes simplex at the concentration of 5, 10 and 20 mu g/ml respectively.

Targets:

Antifection

In vivo:

Biological Sciences 2007: 77(2): 197-205.

Antineoplastic and antiviral activities of pyrrolizidine alkaloids from Heliotropium marifolium Koen. ex Retz[Reference: WebLink]

METHODS AND RESULTS:
From Heliotropium marifolium roots, five pyrrolizidine alkaloids were isolated, characterized by means of their spectral data and/or co-tlc. Except lasiocarpine-N-oxide, the other alkaloids were reported first time from this plant species. The estimation studies revealed that, the heliotrine-N-oxide was major alkaloid both in vivo and in vitro. Among isolated compounds, lasiocarpine-N-oxide demonstrated maximum antineoplastic activity (65.2%) at the concentration of 10 mu g/ kg/day and cytotoxic (36.4%) effects at the concentration of 10 mu g/ml.
CONCLUSIONS:
Supinine, lasiocarpine-N-oxide and europine-N-oxide exhibited virucidal activity to Poliomyelitis, Coxsackie, Semliki forest, Vesicular stomatitis and Herpes simplex at the concentration of 5, 10 and 20 mu g/ml respectively.

Europine N-oxide Description

Source:	The herbs of Cynoglossum officinale L.
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Product Name	Europine N-oxide
Price:
CAS No.:	65582-53-8
Catalog No.:	CFN00265
Molecular Formula:	C₁₆H₂₇NO₇
Molecular Weight:	345.39 g/mol
Purity:	>=98%
Type of Compound:	Alkaloids
Physical Desc.:	Powder
Source:	The herbs of Cynoglossum officinale L.
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS SDF
Similar structural:	Comparison (Web) (SDF)
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Antiviral Compound Library Alkaloids Compound Library Antifection Inhibitor Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	2.8953 mL	14.4764 mL	28.9528 mL	57.9056 mL	72.3819 mL
5 mM	0.5791 mL	2.8953 mL	5.7906 mL	11.5811 mL	14.4764 mL
10 mM	0.2895 mL	1.4476 mL	2.8953 mL	5.7906 mL	7.2382 mL
50 mM	0.0579 mL	0.2895 mL	0.5791 mL	1.1581 mL	1.4476 mL
100 mM	0.029 mL	0.1448 mL	0.2895 mL	0.5791 mL	0.7238 mL

CFN00269	Acetylheliosupine	31514-30-4	439.50	C₂₂H₃₃NO₈
CFN00270	Heliotrine	303-33-3	313.39	C₁₆H₂₇NO₅
CFN00271	Heliotrine N-oxide	6209-65-0	329.39	C₁₆H₂₇NO₆
CFN00275	Macrophylline	27841-97-0	239.31	C₁₃H₂₁NO₃
CFN00264	Europine	570-19-4	329.39	C₁₆H₂₇NO₆
CFN00265	Europine N-oxide	65582-53-8	345.39	C₁₆H₂₇NO₇
CFN00266	Latifoline	6029-86-3	393.44	C₂₀H₂₇NO₇
CFN00267	Latifoline N-oxide	98752-06-8	409.43	C₂₀H₂₇NO₈
CFN00268	Heliosupine	32728-78-2	397.47	C₂₀H₃₁NO₇
CFN00454	Heliosupine N-oxide	31701-88-9	413.5	C₂₀H₃₁NO₈