ChemFaces is a professional high-purity natural products manufacturer.
Product Intended Use
1. Reference standards
2. Pharmacological research
Citing Use of our Products
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Address: No. 83, CheCheng Rd., WETDZ, Wuhan, Hubei 430056, PRC
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* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
|Size /Price /Stock
||10 mM * 1 mL in DMSO / $109.4 / In-stock||Other Packaging
||*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
More articles cited ChemFaces products.
Molecules.2019, 24(6):E1155Pharmacognosy Journal...2019...Ind Crops Prod.2014, 62:173-178Acta Chromatographica2016, 29(3)Nat Commun.2021, 12(1):681.BMC Plant Biol.2018, 18(1):122Malaysian J of Fundamental and Ap...2018...Antioxidants2022, 11(2),234.
Curr Eye Res.2018, 43(1):27-34Int J Mol Sci.2018, 19(2)Journal of Functional Foods...2019...J Med Food.2021, 24(3):209-217.Int J Mol Sci.2022, 23(1):538.Molecules2021, 26(1),230Molecules.2016, 21(10)J. Soc. Cosmet. Sci. Korea2016, 163-171
Int J Mol Sci.2021, 22(16):8604.PLoS One.2020, 15(2):e0220084.Process Biochemistry2019, 87:213-220J of the Korean Society of Cosmet...2019...Food Science and Biotechnology...2015...Invest New Drugs.2017, 35(2):166-179Molecules.2020, 25(23):5609.
Our products had been exported to the following research institutions and universities, And still growing.
Centrum Menselijke Erfelijkheid (Belgium)University of Vienna (Austria)National Research Council of Ca... (Canada)Utah State University (USA)
The Vancouver Prostate Centre (... (Canada)MTT Agrifood Research Finland (Finland)Center for protein Engineering ... (Belgium)CSIRO - Agriculture Flagship (Australia)
Complutense University of Madrid (Spain)University of Ioannina (Greece)Universidad de Ciencias y Artes... (Mexico)
Inquire / Order:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
J Food Sci.2021, 86(9):3810-3823.J Phys Chem Lett.2021, 12(7):1793-1802.Foods.2021, 10(6):1378.J Biochem Mol Toxicol.2020, 34(7):e22489.Pharmaceutical Chemistry Journal2019, 52(12):986-991Environ Toxicol.2021, doi: 10.1002J Pharm Biomed Anal.2021, 196:113931. Appl Microbiol Biotechnol.2018, 102(12):5105-5120Cytotechnology.2017, 69(5):765-773Toxicol In Vitro.2018, 52:94-105
Related Screening Libraries
|| Hesperetin-7-methyl ether is a natural prooduct from Citrus maxima.|
Hesperetin-7-methyl ether Description
||The peels of Citrus maxima
||Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
||Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: email@example.com
||The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.IF=36.216(2019)PMID: 29328914
Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.IF=22.415(2019)PMID: 32004475
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.IF=14.548(2019)PMID: 29149595
ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.IF=13.903(2019)PMID: 29553709
Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.IF=13.297(2019)PMID: 28005066
Sci Adv. 2018 Oct 24;4(10): eaat6994. doi: 10.1126/sciadv.aat6994.IF=12.804(2019)PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
|J Pharm Sci. 2013 Jul;102(7):2120-7. |
|Inhibitory effects of hesperetin derivatives on guinea pig phosphodiesterases and their ratios between high- and low-affinity rolipram binding.[Pubmed: 23666855]|
The phosphodiesterase (PDE)4 molecule exists as two distinct conformers, PDE4H and PDE4L , which have high and low affinities, respectively, for the selective PDE4 inhibitor, rolipram.
The inhibition of PDE4H and PDE4L is associated with adverse responses, such as nausea, vomiting, and gastric hypersecretion, and with anti-inflammatory and bronchodilator effects, respectively.
METHODS AND RESULTS:
We determined the therapeutic (PDE4H/PDE4L) ratios of hesperetin-7-O-methylether(Hesperetin-7-methyl ether), hesperetin-5,7,3'-O-trimethylether (HTME), hesperetin-7-O-acetate, hesperetin-7,3'-O-diacetate, hesperetin-5,7,3'-O-triacetate (HTA), hesperetin-5,7,3'-O-tripropionate, hesperetin-5,7,3'-O-tributyrate, hesperetin-5,7,3'-O-triisobutyrate, and hesperetin-5,7,3'-O-tripivatate, and compared these ratios to those of hesperetin, hesperetin-7,3'-O-dimethylether, hesperidin, and hesperidin-3'-O-methylether to identify derivatives with therapeutic ratios and to characterize the structure-activity relationships among these compounds.