ChemFaces is a professional high-purity natural products manufacturer.
Product Intended Use
1. Reference standards
2. Pharmacological research
3. Inhibitors
Citing Use of our Products
How to Order
Orders via your E-mail:
1. Product number / Name / CAS No.
2. Delivery address
3. Ordering/billing address
4. Contact information
Sent to Email: info@chemfaces.com
Contact Us
Order & Inquiry & Tech Support
Tel: (0086)-27-84237683
Fax: (0086)-27-84254680
E-mail: manager@chemfaces.com
Address: No. 83, CheCheng Rd., WETDZ, Wuhan, Hubei 430056, PRC
Delivery time
Delivery & Payment method
1. Usually delivery time: Next day delivery by 9:00 a.m. Order now
2. We accept: Wire transfer & Credit card & Paypal & Western Union
* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
| Size /Price /Stock |
10 mM * 1 mL in DMSO / $99.2 / In-stock |
Other Packaging |
*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap |
More articles cited ChemFaces products.
Dicle Tip Dergisi2020, 47(2),423-430.World J Mens Health.2019, 10.5534Nat Prod Sci.2019, 25(3):238Front Cell Dev Biol.2021, 9:638174. Processes2021, 9(11),2065.Anal Bioanal Chem....2020...Oncotarget.2015, 6(31):30831-49Journal of Functional Foods...2022...
Antioxidants (Basel).2021, 10(8):1300. Industrial Food Engineering...2015...Plant Direct.2021, 5(4):e00318.Phytochemistry Letters2017, 449-455Cell Mol Biol(Noisy-le-grand)...2019...Acta Physiologiae Plantarum...2015...Journal of Functional Foods...2022...Toxins (Basel).2019, 11(10):E575
J Biomol Struct Dyn.2022, 5;1-17. J Am Soc Mass Spectrom....2021...Environ Toxicol.2020, doi: 10.1002China Pharmacy2015, 26(27)Plants (Basel).2021, 10(5):951.J Food Sci Technol.2022, 59(1):212-219.Oncol Rep.2016, 35(3):1356-64
More...
Our products had been exported to the following research institutions and universities, And still growing.
Universidad Veracuzana (Mexico)University of Liège (Belgium)Florida International University (USA)Lund University (Sweden)
University of East Anglia (United Kingdom)University of the Basque Country (Spain)University of Wisconsin-Madison (USA)University of Helsinki (Finland)
Sanford Burnham Prebys Medical ... (USA)Imperial College London (United Kingdom)University of Sao Paulo (Brazil)
More...
Linderene
Inquire / Order:
manager@chemfaces.com
Technical Inquiries:
service@chemfaces.com
Tel:
+86-27-84237783
Fax:
+86-27-84254680
Address:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Pharmaceutics.2020, 12(9):882. Asian J Beauty Cosmetol2019, 17(3):287-294Neuropharmacology.2018, 131:68-82Sci Rep.2018, 8(1):12970Dicle Tip Dergisi2020, 47(2),423-430.Eur J Pharmacol.2018, 832:96-103Front Pharmacol.2021, 12:770667.Acta horticulturae2017, 1158:257-268Antibiotics.2022, 11(4), 510.Forensic Sci Int.2022, 341:111475.
Related Screening Libraries
| Description: |
Linderene, linderalactone and isolinderalactone inhibit the enzymes from both origins to the same extent. |
Linderene Description
| Source: |
The roots of Lindera aggregata( Sims) Kosterm |
| Solvent: |
Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
| Storage: |
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
|
| After receiving: |
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling. |
ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)PMID: 29328914
Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)PMID: 32004475
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)PMID: 29149595
ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)PMID: 29553709
Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.
IF=13.297(2019)PMID: 28005066
Sci Adv. 2018 Oct 24;4(10): eaat6994. doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
|
1 mg |
5 mg |
10 mg |
20 mg |
25 mg |
| 1 mM |
4.3422 mL |
21.7108 mL |
43.4216 mL |
86.8432 mL |
108.5541 mL |
| 5 mM |
0.8684 mL |
4.3422 mL |
8.6843 mL |
17.3686 mL |
21.7108 mL |
| 10 mM |
0.4342 mL |
2.1711 mL |
4.3422 mL |
8.6843 mL |
10.8554 mL |
| 50 mM |
0.0868 mL |
0.4342 mL |
0.8684 mL |
1.7369 mL |
2.1711 mL |
| 100 mM |
0.0434 mL |
0.2171 mL |
0.4342 mL |
0.8684 mL |
1.0855 mL |
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
| Kinase Assay: |
| Biol Pharm Bull. 2002 Aug;25(8):1049-52. | | Prolyl endopeptidase inhibitors from the roots of Lindera strychnifolia F. Vill.[Pubmed: 12186408] | We studied the PEP inhibitory constituents of the roots of Lindera strychnifolia F. VILL and isolated two known tannins, epicatechin (1) and aesculitannin B (2), and four known sesquiterpenes, Linderene (3), Linderene acetate (4), linderalactone (5) and isolinderalactone (6) as inhibitors.
METHODS AND RESULTS:
On the inhibitory activities of six compounds against PEP from Flavobacterium meningosepticum and that from rat brain supernatant, compounds 1, 2 and Linderene acetate inhibited the enzyme from Flavobacterium more strongly than that from rat brain supernatant. However, Linderene, linderalactone and isolinderalactone inhibited the enzymes from both origins to the same extent and furthermore, compound 6 was the strongest natural inhibitor against PEP from rat brain supernatant.
CONCLUSIONS:
The kinetic study of these inhibitors indicated that compounds 1, 2 are noncompetitive inhibitors and compounds Linderene,linderalactone,isolinderalactone are competitive inhibitors. |
|
Tags: buy Linderene | Linderene supplier | purchase Linderene | Linderene cost | Linderene manufacturer | order Linderene | Linderene distributor
