Murrayanol | CAS:144525-81-5 | Manufacturer ChemFaces

Murrayanol

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Size /Price /Stock	10 mM * 1 mL in DMSO / Inquiry
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Description:

Murrayanol has antioxidant activity. It shows an IC50 of 109 μg/mL against hPGHS-1 and an IC50 of 218 μg/mL against hPGHS-2 in antiinflammatory assays.

Targets:

Topoisomerase | Antifection

In vitro:

J Agric Food Chem. 1999 Feb;47(2):444-7.

Biologically active carbazole alkaloids from Murraya koenigii.[Pubmed: 10563914]

METHODS AND RESULTS:
The bioassay guided fractionation of the acetone extract of the fresh leaves of Murraya koenigii resulted in the isolation of three bioactive carbazole alkaloids, mahanimbine (1), Murrayanol (2), and mahanine (3), as confirmed from their (1)H and (13)C NMR spectral data. Compound 2 showed an IC(50) of 109 microg/mL against hPGHS-1 and an IC(50) of 218 microg/mL against hPGHS-2 in antiinflammatory assays, while compound 1 displayed antioxidant activity at 33.1 microg/mL.
CONCLUSIONS:
All three compounds were mosquitocidal and antimicrobial and exhibited topoisomerase I and II inhibition activities.

Murrayanol Description

Source:	The leaves of Murraya koenigii
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Product Name	Murrayanol
Price:
CAS No.:	144525-81-5
Catalog No.:	CFN92201
Molecular Formula:	C₂₄H₂₉NO₂
Molecular Weight:	363.5 g/mol
Purity:	>=98%
Type of Compound:	Alkaloids
Physical Desc.:	Cryst.
Source:	The leaves of Murraya koenigii
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS SDF Manual
Similar structural:	Comparison (Web) (SDF)
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Anti-inflammatory Compound Library Inhibitors Compound Library Antibacterial Compound Library Insecticides Compound Library Alkaloids Compound Library Topoisomerase Inhibitor Library Antifection Inhibitor Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	2.751 mL	13.7552 mL	27.5103 mL	55.0206 mL	68.7758 mL
5 mM	0.5502 mL	2.751 mL	5.5021 mL	11.0041 mL	13.7552 mL
10 mM	0.2751 mL	1.3755 mL	2.751 mL	5.5021 mL	6.8776 mL
50 mM	0.055 mL	0.2751 mL	0.5502 mL	1.1004 mL	1.3755 mL
100 mM	0.0275 mL	0.1376 mL	0.2751 mL	0.5502 mL	0.6878 mL

CFN91427	Clausine G	186002-62-0	271.3	C₁₅H₁₃NO₄
CFN97428	Clausine Z	866111-14-0	227.2	C₁₃H₉NO₃
CFN97800	Clausine I	182261-94-5	241.24	C₁₄H₁₁NO₃
CFN97796	Clauszoline M	187110-72-1	227.22	C₁₃H₉NO₃
CFN92926	Curryangine	25488-37-3	331.45	C₂₃H₂₅NO
CFN92927	Murrayamine E	172617-68-4	347.45	C₂₃H₂₅NO₂
CFN91189	Koenimbine	21087-98-9	293.4	C₁₉H₁₉NO₂
CFN70319	Koenigicine	24123-92-0	323.4	C₂₀H₂₁NO₃
CFN92197	Mahanimbine	21104-28-9	331.5	C₂₃H₂₅NO
CFN92198	Isomahanimbine	26871-46-5	331.5	C₂₃H₂₅NO