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Noreugenin
Noreugenin
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Noreugenin
Price: $318 / 20mg
CAS No.: 1013-69-0
Catalog No.: CFN99027
Molecular Formula: C10H8O4
Molecular Weight: 192.2 g/mol
Purity: >=98%
Type of Compound: Flavonoids
Physical Desc.: Powder
Source: The rootbark of Schumanniophyton magnificum
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF    Manual
Similar structural: Comparison (Web)  (SDF)
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / $62.3 / In-stock
Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
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Product Use Citation
Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Reference standards.
In vitro:
J Asian Nat Prod Res. 2006 Oct-Nov;8(7):663-70.
Chromone glycosides from Knoxia corymbosa.[Pubmed: 17135054]
Four new chromone glycosides, corymbosins K1-K4 (3-6), together with two known compounds, Noreugenin (1) and undulatoside A (2), were isolated from the whole plant of Knoxiacorymbosa (Rubiaceae).
METHODS AND RESULTS:
The structures of the new compounds were established through extensive NMR or X-ray spectroscopic analysis as 7-O-beta-D-allopyranosyl-5-hydroxy-2-methylchromone (corymbosin K1, 3), 7-O-beta-D-6-acetylglucopyranosyl-5-hydroxy-2-methylchromone (corymbosin K2, 4), 7-O-[6-O-(4-O-trans-caffeoyl-beta-D-allopyranosyl)]-beta-D-glucopyranosyl-5-hydroxy-2-methylchromone (corymbosin K3, 5) and 7-O-[6-O-(4-O-trans-feruloyl-beta-D-allopyranosyl)]-beta-D-glucopyranosyl-5-hydroxy-2- methylchromone (corymbosin K4, 6). Compounds 2-5 were subjected to test their immunomodulatory activity invitro.
Noreugenin Description
Source: The rootbark of Schumanniophyton magnificum
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
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Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

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Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
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ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
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Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 5.2029 mL 26.0146 mL 52.0291 mL 104.0583 mL 130.0728 mL
5 mM 1.0406 mL 5.2029 mL 10.4058 mL 20.8117 mL 26.0146 mL
10 mM 0.5203 mL 2.6015 mL 5.2029 mL 10.4058 mL 13.0073 mL
50 mM 0.1041 mL 0.5203 mL 1.0406 mL 2.0812 mL 2.6015 mL
100 mM 0.052 mL 0.2601 mL 0.5203 mL 1.0406 mL 1.3007 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Planta Med. 1988 Jun;54(3):239-42.
New Chromone Alkaloids from the Stem Bark of Schumanniophyton magnificum.[Pubmed: 17265261]
Fractionation of a methanolic extract of the stem bark of SCHUMANNIOPHYTON MAGNIFICUM yielded large quantities of mannitol. In addition, Noreugenin and ten related chromone alkaloids were isolated. Seven of these alkaloids had been isolated previously from S. MAGNIFICUM and one other from S.PROBLEMATICUM but two of the alkaloids were novel, one was hydroxy- N-methylschumannificine and the other was the acetate of N-demethylrohitukine. The structures of the two alkaloids have been deduced from their spectral features.
CFN958668-C-beta-D-(6-O-galloyl)glucosylnoreugenin152041-17-3506.4C23H22O13
CFN96860Cnidimol A103629-80-7276.28C15H16O5
CFN90808Eugenin480-34-2206.2C11H10O4
CFN961988-Methyleugenitol41682-21-7220.2C12H12O4
CFN975445,7-Dihydroxy-2-isopropylchromone96552-59-9220.2 C12H12O4
CFN892188-Glucosyl-5,7-dihydroxy-2-(1-methylpropyl)chromone188818-27-1396.39C19H24O9
CFN971716-Acetyl-2,2-dimethylchroman-4-one68799-41-7218.3 C13H14O3
CFN968942,5-Dimethylchroman-4-one69687-87-2176.21C11H12O2
CFN89130Altechromone A38412-47-4190.19C11H10O3
CFN98359Cassiachromone28955-30-8232.2 C13H12O4
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