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    Natural Products
    Norjuziphine
    Information
    CAS No. 74119-87-2 Price
    Catalog No.CFN92409Purity>=98%
    Molecular Weight285.3Type of CompoundAlkaloids
    FormulaC17H19NO3Physical DescriptionCryst.
    Download     COA    MSDS    SDFSimilar structuralComparison (Web)  (SDF)
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    Address: No. 83, CheCheng Rd., WETDZ, Wuhan, Hubei 430056, PRC
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    * Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
    According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
    Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
    Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
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    Norjuziphine

    Norjuziphine
    Product Name Norjuziphine
    CAS No.: 74119-87-2
    Catalog No.: CFN92409
    Molecular Formula: C17H19NO3
    Molecular Weight: 285.3 g/mol
    Purity: >=98%
    Type of Compound: Alkaloids
    Physical Desc.: Cryst.
    Source: The tubers of Corydalis incisa
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Price:
    Inquire / Order: manager@chemfaces.com
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  • Int J Oncol.2019, 55(1):320-330
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  • Related Screening Libraries
    Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
    10 mM * 1 mL in DMSO / Inquiry / In-stock
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  • Anti-platelet aggregation Compound Library
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  • Biological Activity
    Description: Norjuziphine has antiplatelet aggregation activity.
    In vitro:
    Planta Med. 2001 Jul;67(5):423-7.
    A new tetrahydroprotoberberine N-oxide alkaloid and anti-platelet aggregation constituents of Corydalis tashiroi.[Pubmed: 11488455]

    METHODS AND RESULTS:
    A new tetrahydroprotoberberine N-oxide alkaloid, (-)-cis-isocorypalmine N-oxide (1), together with two known compounds, 6-methoxydihydrosanguinarine (2) and Norjuziphine (3), were isolated in continuing studies of the entire Formosan Corydalis tashiroi plant.
    CONCLUSIONS:
    The structures of these three compounds were determined through spectral analyses. In addition, compounds 1, 2, 3 and the seven alkaloids previously reported: (-)-cis-corydalmine N-oxide, (-)-trans-corydalmine N-oxide, (-)-trans-isocorypalmine N-oxide, scoulerine, protopine, oxysanguinarine and corydalmine, were found to possess antiplatelet aggregation activity.
    Norjuziphine Description
    Source: The tubers of Corydalis incisa
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 3.5051 mL 17.5254 mL 35.0508 mL 70.1016 mL 87.6271 mL
    5 mM 0.701 mL 3.5051 mL 7.0102 mL 14.0203 mL 17.5254 mL
    10 mM 0.3505 mL 1.7525 mL 3.5051 mL 7.0102 mL 8.7627 mL
    50 mM 0.0701 mL 0.3505 mL 0.701 mL 1.402 mL 1.7525 mL
    100 mM 0.0351 mL 0.1753 mL 0.3505 mL 0.701 mL 0.8763 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    Protocol
    Structure Identification:
    J Nat Prod. 1984 May-Jun;47(3):459-64.
    Additional alkaloids of Pachygone ovata.[Pubmed: 6481360]

    METHODS AND RESULTS:
    Pachygone ovata (Menispermaceae), indigenous to the sandy seashores of southern India, is a woody climber whose fruits have been used as a rodenticide and fish poison. Chromatography of the extract of the roots resulted in the reisolation of the alkaloids liriodenine, coclaurine, trilobine (1), and magnoflorine and the isolation of stepholidine, coreximine, isoboldine, Norjuziphine, and nortrilobine (2).
    CONCLUSIONS:
    Nortrilobine (2) is a new dibenzo-p-dioxin bisbenzylisoquinoline alkaloid whose structure was established by a consideration of spectral data and conversion to isotrilobine (3).
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