Scabertopin | CAS:185213-52-9 | Manufacturer ChemFaces

Scabertopin

ChemFaces products have been cited in many studies from excellent and top scientific journals

Product Name	Scabertopin
Price:	$368 / 20mg
CAS No.:	185213-52-9
Catalog No.:	CFN97798
Molecular Formula:	C₂₀H₂₂O₆
Molecular Weight:	358.39 g/mol
Purity:	>=98%
Type of Compound:	Sesquiterpenoids
Physical Desc.:	Powder
Source:	The herbs of Elephantopus scaber Linn.
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS SDF Manual
Similar structural:	Comparison (Web) (SDF)
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.

Size /Price /Stock	10 mM * 1 mL in DMSO / $114.2 / In-stock
Other Packaging	*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap

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Description:

Scabertopin exhibits significant antitumor effect in vitro in a concentration-dependent manner.

In vitro:

Exp Oncol. 2006 Jun;28(2):106-9.

Antitumor activities of the four sesquiterpene lactones from Elephantopus scaber L.[Pubmed: 16837899]

To evaluate antitumor activity of sesquiterpene lactones (Scabertopin (ES-2), isoScabertopin (ES-3), deoxyelephantopin (ES-4), isodeoxyelephantopin (ES-5)) isolated from Elephantopus scaber L. in vitro and in vivo.
METHODS AND RESULTS:
SMMC-7721, Caco-2 and HeLa cell lines were treated with ES-2,3,4,5. Cell viability was determined by MTT assay. Agarose gel electrophoresis was used to detect DNA fragmentation. To evaluate in vivo antitumor activity of ES-4, experimental murine tumor model was used.
CONCLUSIONS:
It was shown that Scabertopin, ES-4, ES-5 exhibited significant antitumor effect in vitro in a concentration-dependent manner.

Scabertopin Description

Source:	The herbs of Elephantopus scaber Linn.
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Anticancer Compound Library Sesquiterpenoids Compound Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	2.7903 mL	13.9513 mL	27.9026 mL	55.8051 mL	69.7564 mL
5 mM	0.5581 mL	2.7903 mL	5.5805 mL	11.161 mL	13.9513 mL
10 mM	0.279 mL	1.3951 mL	2.7903 mL	5.5805 mL	6.9756 mL
50 mM	0.0558 mL	0.279 mL	0.5581 mL	1.1161 mL	1.3951 mL
100 mM	0.0279 mL	0.1395 mL	0.279 mL	0.5581 mL	0.6976 mL

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