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    Senkyunolide
    Information
    CAS No. 63038-10-8 Price $488 / 20mg
    Catalog No.CFN80253Purity>=98%
    Molecular Weight192.11Type of CompoundMiscellaneous
    FormulaC12H16O2Physical DescriptionOil
    Download COA    MSDSSimilar structuralComparison
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    According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
    Size /Price /Stock 10 mM * 1 mL in DMSO / $27.4 / In-stock
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    Senkyunolide

    Senkyunolide
    Product Name Senkyunolide
    CAS No.: 63038-10-8
    Catalog No.: CFN80253
    Molecular Formula: C12H16O2
    Molecular Weight: 192.11 g/mol
    Purity: >=98%
    Type of Compound: Miscellaneous
    Physical Desc.: Oil
    Source: The roots of Ligusticum chuanxiong hort
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Price: $488 / 20mg
    Download: COA    MSDS
    Similar structural: Comparison
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  • Clin Transl Med.2021, 11(5):e392.
  • Current Topics in Nutraceutical Research2021, 19(1),p90-105.
  • Phytomedicine.2018, 38:45-56
  • Molecules2022, 27(3),1140.
  • Eur J Pharmacol.2020, 889:173589.
  • Ulm University Medical Center2020, doi: 10.18725.
  • Viruses.2017, 9(10)
  • Polytechnic University of Catalonia2017, 105826
  • Natural Product Res.&Deve.2022, 1001-6880.
  • International J of Green Pharmacy2019, 13(3)
  • Related Screening Libraries
    Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
    10 mM * 1 mL in DMSO / Inquiry / In-stock
    Related Libraries
  • Miscellaneous Compound Library
  • Biological Activity
    Description: Reference standards.
    In vitro:
    Chinese Journal of Pharmaceutical Analysis, 2012, 32(9):1644-1647.
    HPLC determination of equilibrium solubility and apparent oil/water partition coefficient of senkyunolide.[Reference: WebLink]
    To determine the equilibrium solubility of senkyunoide and its partition coefficients for the n-octanol-water/buffer solution systems,so as to provide a basis for new formulations designing.
    METHODS AND RESULTS:
    A high performance liquid chromatography method was established to detect the concentration of Senkyunolide .The Megres ODS(5 μm,4.6 mm×100 mm)column was adopted,the mobile phase was acetonitrile-water(1:3, v/v)at a flow rate of 1.0 mL·min-1,and the detection wavelength was 278 nm.The concentration of Senkyunolide in different pH solutions and the partition coefficients for the n-octanol-water and n-octanol-buffer solution systems were detected. The equilibrium solubility reached a maximum of 34.31 mg·mL-1in water at 37°C.Senk yunolide was instable in solvent systems pH≥9.0.Partition coefficient of Senkyunolidewas 13.43(lg P app=1.13) in the n-octanol-water system;there was no significant effect of pH to partition coefficient of Senkyunolide .
    CONCLUSIONS:
    The study showed that Senkyunolide is soluble,the partition coefficient of Senkyunolide is moderate,and the relative molecular mass of Senkyunolide is small.Therefore,we can explain why Senkyunolide can quickly reach into blood and brain.Senkyunolide can be predicted with a good application value.
    Senkyunolide Description
    Source: The roots of Ligusticum chuanxiong hort
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 5.2054 mL 26.0268 mL 52.0535 mL 104.107 mL 130.1338 mL
    5 mM 1.0411 mL 5.2054 mL 10.4107 mL 20.8214 mL 26.0268 mL
    10 mM 0.5205 mL 2.6027 mL 5.2054 mL 10.4107 mL 13.0134 mL
    50 mM 0.1041 mL 0.5205 mL 1.0411 mL 2.0821 mL 2.6027 mL
    100 mM 0.0521 mL 0.2603 mL 0.5205 mL 1.0411 mL 1.3013 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
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