ChemFaces is a professional high-purity natural products manufacturer.
Product Intended Use
1. Reference standards
2. Pharmacological research
3. Inhibitors
Citing Use of our Products
How to Order
Orders via your E-mail:
1. Product number / Name / CAS No.
2. Delivery address
3. Ordering/billing address
4. Contact information
Sent to Email: info@chemfaces.com
Contact Us
Order & Inquiry & Tech Support
Tel: (0086)-27-84237683
Fax: (0086)-27-84254680
E-mail: manager@chemfaces.com
Address: No. 83, CheCheng Rd., WETDZ, Wuhan, Hubei 430056, PRC
Delivery time
Delivery & Payment method
1. Usually delivery time: Next day delivery by 9:00 a.m. Order now
2. We accept: Wire transfer & Credit card & Paypal & Western Union
* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
| Size /Price /Stock |
10 mM * 1 mL in DMSO / $27.4 / In-stock |
Other Packaging |
*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap |
More articles cited ChemFaces products.
Front. Pharmacol.2022, 901563.Phytomedicine.2019, 57:95-104Cancer Manag Res.2019, 11:483-500Biomedicines.2020, 8(11):486.J Microbiol Immunol Infect....2021...Curr Eye Res.2018, 43(1):27-34Journal of Functional Foods...2017...Wageningen University & Research...2018...
PLoS One.2018, 13(3):e0193386Eur J Pharmacol.2021, 906:174220.Phytomedicine.2019, 62:152962Pharmaceuticals (Basel)....2021...Heinrich Heine University Dusseld...2021...Foods.2022, 11(6):882.Int J Nanomedicine.2022, 17:6513-6525.Nutrients.2021, 13(1):254.
Toxicol In Vitro.2023, 86:105521. Journal of Functional Foods...2022...University of Stuttgart2021, 11682.Planta Med.2022, a-1876-3009.Natural Product Communications...2020...Food Chem.2020, 332:127412Antioxidants (Basel).2022, 11(8):1471.
More...
Our products had been exported to the following research institutions and universities, And still growing.
University of Toulouse (France)Celltrion Chemical Research Ins... (Korea)Research Unit Molecular Epigene... (Germany)University of Minnesota (USA)
University of Illinois (USA)University of Perugia (Italy)University of Hertfordshire (United Kingdom)Osmania University (India)
Johannes Gutenberg University M... (Germany)Universite Libre de Bruxelles (Belgium)University of the Basque Country (Spain)
More...
Senkyunolide
Inquire / Order:
manager@chemfaces.com
Technical Inquiries:
service@chemfaces.com
Tel:
+86-27-84237783
Fax:
+86-27-84254680
Address:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Clin Transl Med.2021, 11(5):e392.Current Topics in Nutraceutical Research2021, 19(1),p90-105.Phytomedicine.2018, 38:45-56Molecules2022, 27(3),1140.Eur J Pharmacol.2020, 889:173589.Ulm University Medical Center2020, doi: 10.18725.Viruses.2017, 9(10)Polytechnic University of Catalonia2017, 105826Natural Product Res.&Deve.2022, 1001-6880.International J of Green Pharmacy2019, 13(3)
Related Screening Libraries
| Size /Price /Stock |
10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
|
Related Libraries |
Miscellaneous Compound Library |
| Description: |
Reference standards. |
| In vitro: |
| Chinese Journal of Pharmaceutical Analysis, 2012, 32(9):1644-1647. | | HPLC determination of equilibrium solubility and apparent oil/water partition coefficient of senkyunolide.[Reference: WebLink] | To determine the equilibrium solubility of senkyunoide and its partition coefficients for the n-octanol-water/buffer solution systems,so as to provide a basis for new formulations designing.
METHODS AND RESULTS:
A high performance liquid chromatography method was established to detect the concentration of Senkyunolide .The Megres ODS(5 μm,4.6 mm×100 mm)column was adopted,the mobile phase was acetonitrile-water(1:3, v/v)at a flow rate of 1.0 mL·min-1,and the detection wavelength was 278 nm.The concentration of Senkyunolide in different pH solutions and the partition coefficients for the n-octanol-water and n-octanol-buffer solution systems were detected. The equilibrium solubility reached a maximum of 34.31 mg·mL-1in water at 37°C.Senk yunolide was instable in solvent systems pH≥9.0.Partition coefficient of Senkyunolidewas 13.43(lg P app=1.13) in the n-octanol-water system;there was no significant effect of pH to partition coefficient of Senkyunolide .
CONCLUSIONS:
The study showed that Senkyunolide is soluble,the partition coefficient of Senkyunolide is moderate,and the relative molecular mass of Senkyunolide is small.Therefore,we can explain why Senkyunolide can quickly reach into blood and brain.Senkyunolide can be predicted with a good application value. |
|
Senkyunolide Description
| Source: |
The roots of Ligusticum chuanxiong hort |
| Solvent: |
Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
| Storage: |
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
|
| After receiving: |
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling. |
ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)PMID: 29328914
Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)PMID: 32004475
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)PMID: 29149595
ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)PMID: 29553709
Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.
IF=13.297(2019)PMID: 28005066
Sci Adv. 2018 Oct 24;4(10): eaat6994. doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
|
1 mg |
5 mg |
10 mg |
20 mg |
25 mg |
| 1 mM |
5.2054 mL |
26.0268 mL |
52.0535 mL |
104.107 mL |
130.1338 mL |
| 5 mM |
1.0411 mL |
5.2054 mL |
10.4107 mL |
20.8214 mL |
26.0268 mL |
| 10 mM |
0.5205 mL |
2.6027 mL |
5.2054 mL |
10.4107 mL |
13.0134 mL |
| 50 mM |
0.1041 mL |
0.5205 mL |
1.0411 mL |
2.0821 mL |
2.6027 mL |
| 100 mM |
0.0521 mL |
0.2603 mL |
0.5205 mL |
1.0411 mL |
1.3013 mL |
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Tags: buy Senkyunolide | Senkyunolide supplier | purchase Senkyunolide | Senkyunolide cost | Senkyunolide manufacturer | order Senkyunolide | Senkyunolide distributor
