Science | Nature | Cell | View More
Natural Products
Stylopine hydrochloride
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Stylopine hydrochloride
Price:
CAS No.: 96087-21-7
Catalog No.: CFN96656
Molecular Formula: C19H18ClNO4
Molecular Weight: 359.81 g/mol
Purity: >=98%
Type of Compound: Alkaloids
Physical Desc.: Powder
Source: The leaves of Chelidonium majus L.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS
Similar structural: Comparison (Web)  (SDF)
Guestbook:
Contact Us
Order & Inquiry & Tech Support

Tel: (0086)-27-84237683
Tech: service@chemfaces.com
Order: manager@chemfaces.com
Address: 176, CheCheng Eest Rd., WETDZ, Wuhan, Hubei 430056, PRC
How to Order
Orders via your E-mail:

1. Product number / Name / CAS No.
2. Delivery address
3. Ordering/billing address
4. Contact information
Order: manager@chemfaces.com
Delivery time
Delivery & Payment method

1. Usually delivery time: Next day delivery by 9:00 a.m. Order now

2. We accept: Wire transfer & Credit card & Paypal
Citing Use of our Products
* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
Our products had been exported to the following research institutions and universities, And still growing.
  • Shanghai Institute of Biochemis... (China)
  • University of Hull (United Kingdom)
  • University of Medicine and Phar... (Romania)
  • Utrecht University (Netherlands)
  • University of Wisconsin-Madison (USA)
  • Nanjing University of Chinese M... (China)
  • The Vancouver Prostate Centre (... (Canada)
  • Universidade do Porto (Portugal)
  • University of Maryland (USA)
  • University of Virginia (USA)
  • The Ohio State University (USA)
  • More...
Package
Featured Products
Irisflorentin

Catalog No: CFN99788
CAS No: 41743-73-1
Price: $40/20mg
Anethole

Catalog No: CFN98550
CAS No: 104-46-1
Price: $30/20mg
Polyphyllin D

Catalog No: CFN90255
CAS No: 50773-41-6
Price: $118/20mg
Benzoylpaeoniflorin

Catalog No: CFN99536
CAS No: 38642-49-8
Price: $80/20mg
Eriodictyol-7-O-glucoside

Catalog No: CFN97865
CAS No: 38965-51-4
Price: $218/10mg
Galangin

Catalog No: CFN98918
CAS No: 548-83-4
Price: $40/20mg
Sesamin

Catalog No: CFN97034
CAS No: 607-80-7
Price: $40/20mg
Decursinol angelate

Catalog No: CFN93173
CAS No: 130848-06-5
Price: $ / mg
Magnolin

Catalog No: CFN98391
CAS No: 31008-18-1
Price: $70/20mg
Rhamnocitrin

Catalog No: CFN97724
CAS No: 569-92-6
Price: $268/10mg
Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Stylopine is a protoberberine-type alkaloid that has potential biological activities, including anti-inflammatory activity.
In vitro:
Arch Pharm Res. 2004 Sep;27(9):923-9.
Stylopine from Chelidonium majus inhibits LPS-induced inflammatory mediators in RAW 264.7 cells.[Pubmed: 15473662]
Stylopine is a major component of the leaf of Chelidonium majus L. (Papaveraceae), which has been used for the removal of warts, papillomas and condylomas, as well as the treatment of liver disease, in oriental countries.
METHODS AND RESULTS:
Stylopine per se had no cytotoxic effect in unstimulated RAW 264.7 cells, but concentration-dependently reduced nitric oxide (NO), prostaglandin E2 (PGE2), tumor necrosis factor-alpha (TNF-alpha) and interleukin-1beta (IL-1beta), and the IL-6 production and cyclooxygenase-2 (COX-2) activity caused by the LPS stimulation. The levels of inducible nitric oxide synthase (iNOS) and COX-2 protein expressions were markedly suppressed by stylopine in a concentration dependent manner.
CONCLUSIONS:
These results suggest that stylopine suppress the NO and PGE2 production in macrophages by inhibiting the iNOS and COX-2 expressions. These biological activities of stylopine may contribute to the anti-inflammatory activity of Chelidonium majus.
Stylopine hydrochloride Description
Source: The leaves of Chelidonium majus L.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
ChemFaces New Products and Compounds
Vicinin 2

Catalog No: CFN95249
CAS No: 90456-53-4
Price: $368/5mg
Citrusin B

Catalog No: CFN95178
CAS No: 105279-10-5
Price: $388/5mg
Methyl ganoderate A

Catalog No: CFN95550
CAS No: 105742-78-7
Price: $413/5mg
Licoflavanone

Catalog No: CFN95213
CAS No: 119240-82-3
Price: $413/5mg
Ampelopsin G

Catalog No: CFN95148
CAS No: 151487-09-1
Price: $318/5mg
Isoformononetin

Catalog No: CFN95024
CAS No: 486-63-5
Price: $318/10mg
Mahuannin G

Catalog No: CFN95553
CAS No: N/A
Price: $318/5mg
Toddalolactone 3'-O-methyl ether (...

Catalog No: CFN95372
CAS No: 143614-35-1
Price: $318/10mg
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.7792 mL 13.8962 mL 27.7924 mL 55.5849 mL 69.4811 mL
5 mM 0.5558 mL 2.7792 mL 5.5585 mL 11.117 mL 13.8962 mL
10 mM 0.2779 mL 1.3896 mL 2.7792 mL 5.5585 mL 6.9481 mL
50 mM 0.0556 mL 0.2779 mL 0.5558 mL 1.1117 mL 1.3896 mL
100 mM 0.0278 mL 0.139 mL 0.2779 mL 0.5558 mL 0.6948 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Irisflorentin

Catalog No: CFN99788
CAS No: 41743-73-1
Price: $40/20mg
Anethole

Catalog No: CFN98550
CAS No: 104-46-1
Price: $30/20mg
Polyphyllin D

Catalog No: CFN90255
CAS No: 50773-41-6
Price: $118/20mg
Benzoylpaeoniflorin

Catalog No: CFN99536
CAS No: 38642-49-8
Price: $80/20mg
Eriodictyol-7-O-glucoside

Catalog No: CFN97865
CAS No: 38965-51-4
Price: $218/10mg
Galangin

Catalog No: CFN98918
CAS No: 548-83-4
Price: $40/20mg
Sesamin

Catalog No: CFN97034
CAS No: 607-80-7
Price: $40/20mg
Decursinol angelate

Catalog No: CFN93173
CAS No: 130848-06-5
Price: $ / mg
Magnolin

Catalog No: CFN98391
CAS No: 31008-18-1
Price: $70/20mg
Rhamnocitrin

Catalog No: CFN97724
CAS No: 569-92-6
Price: $268/10mg
Tags: buy Stylopine hydrochloride | Stylopine hydrochloride supplier | purchase Stylopine hydrochloride | Stylopine hydrochloride cost | Stylopine hydrochloride manufacturer | order Stylopine hydrochloride | Stylopine hydrochloride distributor