Natural Products
| Catalog No. | Information |
| CFN90644 | Sibiricaxanthone B Sibiricaxanthone B is a natural product from Polygala tenuifolia. |
| CFN93002 | Isokaempferide Isokaempferide shows hepatoprotective, antiproliferative, and anti-inflammatory effects, the anti-inflammatory effects can be explained, at least in part, by reducing neutrophil degranulation, myeloperoxidase activity, mediators as well as TNF-alpha secretion. Isokaempferide is used as a bronchodilator, can induce relaxation of guinea-pig isolated trachea. |
| CFN90643 | Mirificin |
| CFN90642 | Forsythoside E |
| CFN90640 | Puerarin 6''-O-xyloside Puerarin 6''-O-xyloside possesses significant anti-osteoporotic activity on ovariectomy mice, it has significant antitumour activities, the mechanisms are related to increased levels of caspase-3, caspase-7, caspase-9 and Bax, and reduced levels Bcl-2. |
| CFN90635 | Saikosaponin F Saikosaponin F shows anti-inflammatory effect against carrageenan-induced plantar oedema in the rat. |
| CFN90634 | Hypaphorine Hypaphorine is an indole-3-acetic acid antagonist which specifically compete with indole-3-acetic acid in binding to the indole-3-acetic acid-binding site in plant peroxidases.Hypaphorine and endogenous indole-3-acetic acid counteract in controlling root hair elongation. |
| CFN90633 | Thonningianin A Thonningianin A represents a new potent glutathione S-transferase in vitro inhibitor. Thonningianin A has anti-cancer and antioxidant properties, involves radical scavenging, anti-superoxide formation and metal chelation. |
| CFN90630 | Quercetin-3-O-sophoroside Quercetin-3-O-sophoroside is the natural ligand of Bet v 1. |
| CFN90629 | Tussilagone Tussilagone has anti-cancer, anti-oxidant and anti-inflammatory activities. Tussilagone inhibits dendritic cell function through the induction of heme oxygenase-1; it has potential treatment of neuro-inflammatory diseases through the inhibition of overproduction of nitric oxide and prostaglandin E(2). |
| CFN90624 | Sinapine thiocyanate Sinapine thiocyanate has antioxidant activities and is hepatoprotective in a dose-dependent manner, implies that Brassica rapa seeds could be developed as a functional food for hepatoprotection. |
| CFN90620 | Alnustone Alnustone has anti-inflammatory, antihepatotoxic and antiemetic activities, |
| CFN90619 | Ecliptasaponin D Reference standards. |
| CFN90617 | Hirsutine Hirsutine has anticancer, cardioprotective, anti‑hypertensive and anti-arrhythmic activities, it also has vasodilatation activity, the mechanism is related to blockade of Ca2+ influx through L-type Ca2+ channels and inhibition of intracellular Ca2+ release may have no relationship with K+ channels. Hirsutine reduces the production of various neurotoxic factors in activated microglial cells and possesses neuroprotective activity in a model of inflammation-induced neurotoxicity. |
| CFN90615 | Hirsuteine Hirsuteine exhibits potent neuroprotective effects against glutamate-induced HT22 cell death. Hirsuteine non-competitively antagonizes nicotine-evoked dopamine release by blocking ion permeation through nicotinic receptor channel complexes. |
| CFN90590 | Cnidilin Cnidilin has high BBB permeability and has pharmacokinetic potentials for the treatment of central nervous system diseases. |
| CFN90582 | (-)-Isocorypalmine (-)-Isocorypalmine has significant antifungal activity. l-isocorypalmine acts as a D1 partial agonist and a D2 antagonist to produce its in vivo effects and may be a promising agent for treatment of cocaine addiction. |
| CFN90581 | Columbamine Columbamine exerts anti-proliferative and anti-vasculogenic effects on metastatic human osteosarcoma U2OS cells with low toxicity. It shows strong acetylcholinesterase (AChE) inhibitory activity with IC50 48.1 μM. |
| CFN90578 | 3,6'-Disinapoyl sucrose 3,6'-Disinapoyl sucrose has neuroprotective effect and antidepressive activity in rats, at least in part, by increasing expression of cyclic AMP response element (CRE)-binding protein (CREB) and its downstream target protein, brain-derived neurotrophic factor (BDNF). 3,6'-Disinapoyl sucrose protect neuron cells from glutamate-induced excitotoxicity include the downregulation of proapoptotic gene Bax and the upregulation of antiapoptotic gene Bcl-2. |
| CFN90577 | Dehydrotrametenolic acid Dehydrotrametenolic acid is a promising candidate for a new type of insulin-sensitizing drug; it can be a potential anticancer agent against H-ras transformed tumor. |
| CFN96098 | Randaiol Randaiol is a natural product from Magnolia hypoleuca. |
| CFN96094 | Gamma-Methoxyisoeugenol Methyl Isoeugenol has antioxidant activity. |
| CFN96027 | Falcarinol Falcarinol has effects on CaCo-2 cells appear to be biphasic, inducing pro-proliferative and apoptotic characteristics at low and high concentrations of Falcarinol, respectively. Falcarinol-associated dermatitis is due to antagonism of the CB(1) receptor in keratinocytes, leading to increased chemokine expression and aggravation of histamine action. |
| CFN90566 | 7-Methoxycoumarin 7-Methoxycoumarin, also known as Herniarin, has potent antioxidant, hepatoprotective, and antitumor effects. 7-Methoxycoumarin has a weak estrogenic activity in vitro and in vivo, it could be beneficial with regard to vagina dryness as it showed a tissue specific effect without exposing the uterus to a potential tumorigenic growth. |
| CFN90565 | Ginsenoside Rg6 Ginsenoside Rg6 can inhibit JK cell proliferation in human lymphocytoma and induce its apoptosis, the mechanism may through mitochondrial dysfunction and an increase of Bax expression and decrease of Bcl-2 expression. |
| CFN96004 | 16-Epikoumidine Reference standards. |
| CFN96001 | 7,2',4'-Trihydroxy-5-methoxy-3-phenylcoumarin Reference standards. |
| CFN97964 | (+)-Lyoniresinol 9'-O-glucoside Reference standards. |
| CFN97963 | Citropten Citropten and valproic acid show antiproliferative effects against A2058 human melanoma cells. |
| CFN90597 | Tracheloside Tracheloside significantly decreases the activity of alkaline phosphatase (AP), an estrogen-inducible marker enzyme, with an IC(50) value of 0.31 microg/ml, a level of inhibition comparable to that of tamoxifen (IC(50) = 0.43 microg/ml). |
| CFN90598 | Trachelogenin Trachelogenin has antiproliferative effect, the mechanism is related to affect the phosphorylation of key proteins such as β-Catenin, c-Myc and GSK3 in the β-Catenin signaling pathway in a concentration-dependent manner. |
| CFN92887 | Euphorbia factor L9 Reference standards. |
| CFN92886 | Euphorbia factor L8 Reference standards. |
| CFN92885 | Euphorbia factor L7a Reference standards. |
| CFN92883 | Euphorbia factor L1 Euphorbia factor L1 inhibits osteoclastogenesis and induces osteoclast apoptosis, it can enhance the ATP hydrolysis activity of ABCB1 stimulated by verapamil. Euphorbia factor L1 inhibits the efflux of ABCB1 in KBv200 and MCF-7/adr cells, does not downregulate their expression either in mRNA or protein level. |
| CFN92882 | Ebracteolata cpd B |
| CFN92855 | 4',7-Dihydroxyflavone 4',7-Dihydroxyflavone can induce transcription of nodulation (nod) genes in Rhizobium meliloti. It has inhibitory activities against COX-2. |
| CFN92838 | Poricoic acid A(F) Poricoic acid A(F) shows anti-inflammatory activity. It is a potential whitening active ingredient, it exhibits good inhibitory effects on the activities of monophenolase and diphenolase in mushroom tyrosinase, as well as a certain inhibitory effect on tyrosinase in B16 cells. |
| CFN92837 | Dehydrotumulosic acid Dehydrotumulosic acid shows anti-inflammatory activity. |
| CFN92836 | Peroxydehydrotumulosic acid 5alpha,8alpha-Peroxydehydrotumulosic acid exhibits inhibitory effects against the Epstein-Barr virus early antigen (EBV-EA) activation induced by 12-O-tetradecanoylphorbol-13-acetate (TPA) in Raji cells. |
| CFN92826 | Cis-N-Feruloyltyramine Cis-N-Feruloyltyramine shows cytotoxicity against the P-388 cancer cell line. N-cis-Feruloyltyramine and N-trans-Feruloyltyramine are the inhibitors of in vitro prostaglandin (PG) synthesis. |
| CFN97865 | Eriodictyol-7-O-glucoside Eriodictyol-7-O-glucoside and epicatechin appears to be responsible for the antioxidant activity of pistachio skin.Eriodictyol-7-O-glucoside has protective effect on cisplatin-induced toxicity was investigated in a human renal mesangial cell line, HRMC; it also can activate Nrf2/ARE signaling, directly associated with its neuroprotection against oxidative stress-induced ischemic; suggests that targeting the Nrf2/ARE pathway may be a promising approach for therapeutic intervention in stroke. |
| CFN92818 | Ginsenoside Rk2 Ginsenoside Rk1 has anti-tumor, and anti-platelet aggregation activities. Ginsenoside Rk1 can strongly inhibit permeability induced by VEGF, advance glycation end-product, thrombin, or histamine in human retinal endothelial cells, it reduces the vessel leakiness of retina in a diabetic mouse model; this anti-permeability activity of Rk1 is correlated with enhanced stability and positioning of tight junction proteins at the boundary between cells; Rk1 induces phosphorylation of myosin light chain and cortactin, which are critical regulators for the formation of the cortical actin ring structure and endothelial barrier. |
| CFN92810 | Dihydrosanguinarine Dihydrosanguinarine has antifungal and anticancer activity.Dihydrosanguinarine at concentrations from 5 microM induced primarily necrosis, whereas apoptosis occurred at 10 microM and above. Dihydrosanguinarine has potential application in the therapy of serious infection caused by I. multifiliis. |
| CFN92809 | Isosakuranin Isosakuranin is a product from Paliurus ramosissimus. |
| CFN92806 | 3,4'-Di-O-methylellagic acid Reference standards. |
| CFN92800 | Qianhucoumarin G Qianhucoumarin G is a natural product from Peucedanum praeruptorum. |
| CFN92799 | cis-Khellactone cis-Khellactone is a natural product from Angelica sinensis. |
| CFN92798 | Panaxydiol Panaxydiol can inhibit rat liver cholesterol acyltransferase (ACAT) with IC50 values of 45 microM. |
| CFN92792 | Curculigoside C Standard reference |
