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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
|Size /Price /Stock
||10 mM * 1 mL in DMSO / $111.4 / In-stock||Other Packaging
||*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
More articles cited ChemFaces products.
J. of Med. Plant Research.2013, 90-151Pharmacogn Mag.2015, 11:S585-91Acta Biochim Pol.2015, 62(2):253-8Mediators Inflamm. 2016, 2016:6189590Pharm Biol.2016, 54(7):1255-62Tropical J. of Pha. Research...2017...Front Aging Neurosci.2018, 10:269Anal Chim Acta.2018, 1039:162-171
Food Quality and Safety2018, 2:213-219J of Health Science and Alternati...2019...Front Pharmacol.2019, 10:1226Int J Mol Sci.2019, 20(9):E2244Phytomedicine.2019, 56:48-56Plos One.2019, 15(2):e0220084J Mater Chem B.2019, 7(39):5896-5919Biomolecules.2020, 10(2):E184
Plant Foods Hum Nutr.2020, 10.1007Food Research International2020, 108987Biomed Pharmacother.2020, 131:110673.iScience.2020, 23(2):100849.Bioorg Med Chem.2020, 28(12):115553.J Biochem Mol Toxicol....2020...Phytochemistry.2021, 181:112539.
Our products had been exported to the following research institutions and universities, And still growing.
Yale University (USA)University of Sao Paulo (Brazil)Leibniz-Institut für Pflanzenb... (Germany)Warszawski Uniwersytet Medyczny (Poland)
Universiti Kebangsaan Malaysia (Malaysia)Kyoto University (Japan)MTT Agrifood Research Finland (Finland)Kazusa DNA Research Institute (Japan)
Florida A&M University (USA)University of Virginia (USA)Molecular Biology Institute of ... (Spain)
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Horticulturae2020, 6(4),76.Front Pharmacol.2019, 10:1025J of Health Science and Alternative Medicine2019, 1(1)J Nat Med.2017, 71(2):457-462Appl. Sci.2020, 10(5),1713.Korean Journal of Pharmacognosy.2019, 50(1):65-71Nutrients.2017, 10(1)Pest Manag Sci.2019, 75(9):2530-2541Molecules.2019, 24(24),4583Front Pharmacol.2019, 10:1226
Related Screening Libraries
|Size /Price /Stock
||10 mM * 100 uL in DMSO / Inquiry / In-stock |
10 mM * 1 mL in DMSO / Inquiry / In-stock
||Xanthones Compound Library
|| Sibiricaxanthone B is a natural product from Polygala tenuifolia.|
|J Sep Sci. 2017 May;40(10):2131-2140. |
|Ultra-fast liquid chromatography with tandem mass spectrometry determination of eight bioactive components of Kai-Xin-San in rat plasma and its application to a comparative pharmacokinetic study in normal and Alzheimer's disease rats.[Pubmed: 28342292]|
|A method of ultra-fast liquid chromatography with tandem mass spectrometry was developed and validated for the simultaneous quantitation of eight bioactive components, including polygalaxanthone III, Sibiricaxanthone B, tenuifolin, sibiricose A5, sibiricose A6, tenuifoliside A, ginsenoside Re and ginsenoside Rb1 in rat plasma after oral administration of Kai-Xin-San.
METHODS AND RESULTS:
The plasma samples were extracted by liquid-liquid extraction using digoxin as an internal standard. Chromatographic separation was performed on a Venusil MP C18 column (100 mm × 2.1 mm, 3 μm) with methanol and 0.05% acetic acid in water as mobile phase. The tandem mass spectrometric detection was performed in the multiple reaction monitoring with turbo ion spray source in the negative ionization. Validation parameters were within acceptable ranges. The established method has been successfully applied to compare the pharmacokinetic profiles of the analytes between normal and Alzheimer's disease rats.
The results indicated that there were significant differences in pharmacokinetic parameters of some components between two groups, which may be due to the mechanisms of Alzheimer's disease and pharmacological effects of the analytes. The pharmacokinetic research in the pathological state might provide more useful information to guide the clinical usage of herbal medicine.
Sibiricaxanthone B Description
||The roots of Polygala tenuifolia
||DMSO, Pyridine, Methanol, Ethanol, etc.
||Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: firstname.lastname@example.org
||The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.IF=36.216(2019)PMID: 29328914
Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.IF=22.415(2019)PMID: 32004475
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.IF=14.548(2019)PMID: 29149595
ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.IF=13.903(2019)PMID: 29553709
Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.IF=13.297(2019)PMID: 28005066
Sci Adv. 2018 Oct 24;4(10): eaat6994. doi: 10.1126/sciadv.aat6994.IF=12.804(2019)PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
|《Journal of Shenyang Pharmaceutical University》 2010-10 |
|Separation and identification of new sucrose esters from root of Polygala tenuifolia Willd.[Reference: WebLink]|
|To study the constituents of the extract from the root of Polygala tenuifolia Willd.|
METHODS AND RESULTS:
The chemical constituents were isolated by silica,Sephadex LH-20 gel column chromatography and HPLC.Chemical characters and spectroscopic analysis were employed for the structural identification.Eleven compounds were obtained and their structures were identified as sibiricose A5(1),tenuifolioside A(α-D-glucopyranoside,3-O-[(2Z)-3-(4-hydroxy-3-methoxyphenyl)-1-oxo-2-propen-1-yl]-β-D-fructofuranosyl,2),tenuifolioside B(α-D-glucopyranoside,3-O-[(2E)-3-(3,4-dimethoxyphenyl)-1-oxo-2-propen-1-yl]-β-D-fructofuranosyl,3),tenuifolioside C(α-D-glucopyranoside,3-O-[(2Z)-3-(3,4-dimethoxyphenyl)-1-oxo-2-propen-1-yl]-β-D-fructofuranosyl,4),sibiricose A6(5),glomeratose A(6),Sibiricaxanthone B(7),polygalaxanthone Ⅺ(8),1,2,3,7-tetramethoxyxanthone(9),onjixanthoneⅡ(10),and polygitol(11).
Compounds 24,named tenuifolioside A-C respectively,are new sucrose esters which have not been reported before.