Natural Products
| Catalog No. | Information |
| CFN90615 | Hirsuteine Hirsuteine exhibits potent neuroprotective effects against glutamate-induced HT22 cell death. Hirsuteine non-competitively antagonizes nicotine-evoked dopamine release by blocking ion permeation through nicotinic receptor channel complexes. |
| CFN90616 | Ajugasterone C Ajugasterone C shows significant inhibitory effect at 100 mg/kg dose on rat paw oedema development due to carrageenan-induced inflammation in Sprague Dawley rats. |
| CFN90617 | Hirsutine Hirsutine has anticancer, cardioprotective, anti‑hypertensive and anti-arrhythmic activities, it also has vasodilatation activity, the mechanism is related to blockade of Ca2+ influx through L-type Ca2+ channels and inhibition of intracellular Ca2+ release may have no relationship with K+ channels. Hirsutine reduces the production of various neurotoxic factors in activated microglial cells and possesses neuroprotective activity in a model of inflammation-induced neurotoxicity. |
| CFN90618 | Swertianolin Swertianolin shows anti-acetylcholinesterase activity effects, it shows significant hepatoprotective effect in the liver damage model induced by alpha-naphthylisot hiocyanate. Swertianolin can scavenge superoxide and hydroxyl radicals with the studying method of the autoxidation of Pyrogallol and afenton. |
| CFN90619 | Ecliptasaponin D Reference standards. |
| CFN90620 | Alnustone Alnustone has anti-inflammatory, antihepatotoxic and antiemetic activities, |
| CFN90621 | Swertisin Swertisin, a novel herbal biomolecule, shows a strong antihyperglycemic action, it provides low cost and readily available differentiating agent that can be translated as a therapeutic tool for effective treatment in diabetes. |
| CFN90622 | Valechlorine Valeranone shows antileishmanial and cytotoxic activity. |
| CFN90623 | Goitrin Goitrin is a potent antithyroid compound, it is a moderate inhibitor of purified bovine adrenal dopamine beta-hydroxylase,leads to a depression of brain norepinephrine and to an elevation of heart and adrenal dopamine. Goitrin is responsible for the induction of glutathione S-transferases. |
| CFN90624 | Sinapine thiocyanate Sinapine thiocyanate has antioxidant activities and is hepatoprotective in a dose-dependent manner, implies that Brassica rapa seeds could be developed as a functional food for hepatoprotection. |
| CFN90625 | Isodemethylwedelolacton Isodemethylwedelolactone is a natural product from the Eclipta prostrata. |
| CFN90626 | Beta,beta-Dimethylacrylalkannin Beta,beta-Dimethylacrylalkannin has radical scavenging activity, it exhibits inhibitory activities on PTP1B with IC50 values of 0.36±0.08 umol·L-1, it may be a new type of leading compounds for the treatment of diabetes. Beta,beta-Dimethylacrylalkannin has great potential as topo I inhibitors compared to other compounds and CPT-11, with 2-3uM inhibition value. Beta,beta-Dimethylacrylalkannin can be potential therapeutics against tumor cell growth because of its unique DNA damaging abilities additional to enzyme inhibition similar to those of doxorubicin. |
| CFN90627 | Heterophyllin B Heterophyllin B is used as the quality control index for evaluating P. heterophylla in the Chinese Pharmacopoeia.Heterophyllin B effectively suppresses the adhesion and invasion of the human esophageal carcinoma cells by mediating the PI3K/AKT/β-catenin pathways and regulating the expression levels of adhesion- and invasion-associated genes. |
| CFN90628 | Asarinin Asarinin, a mammalian lignan precursor, has immunosuppression activity and can inhibit acute rejection in vitro. Asarinin may have a role on TLR4 pathway and produce prolongation of allograft heart survival. Asarinin induces dopamine biosynthesis via activation of the PKA-CREB-TH system and protects against 6-OHDA-induced cytotoxicity by inhibiting the sustained activation of the ERK-p38MAPK-JNK1/2-caspase-3 system in PC12 cells. |
| CFN90629 | Tussilagone Tussilagone has anti-cancer, anti-oxidant and anti-inflammatory activities. Tussilagone inhibits dendritic cell function through the induction of heme oxygenase-1; it has potential treatment of neuro-inflammatory diseases through the inhibition of overproduction of nitric oxide and prostaglandin E(2). |
| CFN90630 | Quercetin-3-O-sophoroside Quercetin-3-O-sophoroside is the natural ligand of Bet v 1. |
| CFN90631 | 6''-O-Malonylgenistin 6''-O-Malonylgenistin possesses a hepatoprotective activity. |
| CFN90632 | Tomatidine Tomatidine shows antibiotic, and anti-inflammatory activities, it significantly suppresses the activity of ACAT and leads to reduction of atherogenesis. Tomatidine inhibits the invasion of A549 cells by reducing the expression of MMPs, also inhibits ERK and Akt signaling pathways and NF-κB activity, suggests a new therapeutic potential for Tomatidine in anti-metastatic therapy. |
| CFN90633 | Thonningianin A Thonningianin A represents a new potent glutathione S-transferase in vitro inhibitor. Thonningianin A has anti-cancer and antioxidant properties, involves radical scavenging, anti-superoxide formation and metal chelation. |
| CFN90634 | Hypaphorine Hypaphorine is an indole-3-acetic acid antagonist which specifically compete with indole-3-acetic acid in binding to the indole-3-acetic acid-binding site in plant peroxidases.Hypaphorine and endogenous indole-3-acetic acid counteract in controlling root hair elongation. |
| CFN90635 | Saikosaponin F Saikosaponin F shows anti-inflammatory effect against carrageenan-induced plantar oedema in the rat. |
| CFN90636 | 14-Hydroxy sprengerinin C 14-Hydroxy sprengerinin C is a natural product from Ophiopogon japonicus. |
| CFN90637 | Cixiophiopogon A Cixiophiopogon A is a natural product from Ophiopogon japonicus. |
| CFN90638 | Ophiogenin-3-O-alpha-L-rhaMnopyranosyl-(1->2)-beta-D-glucopyranoside Ophiogenin-3-O-alpha-L-rhaMnopyranosyl-(1->2)-beta-D-glucopyranoside Description is a natural product from Ophiopogon japonicus. |
| CFN90639 | Linderene Linderene, linderalactone and isolinderalactone inhibit the enzymes from both origins to the same extent. |
| CFN90640 | Puerarin 6''-O-xyloside Puerarin 6''-O-xyloside possesses significant anti-osteoporotic activity on ovariectomy mice, it has significant antitumour activities, the mechanisms are related to increased levels of caspase-3, caspase-7, caspase-9 and Bax, and reduced levels Bcl-2. |
| CFN90641 | Euphorbiasteroid Euphorbiasteroid has anti-obesity activities, it inhibits adipogenesis of 3T3-L1 cells through activation of the AMPK pathway. Euphorbiasteroid could be a transport substrate for P-gp that can effectively inhibit P-gp-mediated drug transport and reverse resistance to anticancer drugs in MES-SA/Dx5 cells; it induces HL-60 cells to apoptosis via promoting Bcl-2/Bax apoptotic signaling pathway in a dose-dependent manner. |
| CFN90642 | Forsythoside E |
| CFN90643 | Mirificin |
| CFN90892 | Hispidulin 7-O-neohesperidoside Hispidulin 7-O-neohesperidoside is one of the active substances responsible for the protective effects of this plant. |
| CFN93002 | Isokaempferide Isokaempferide shows hepatoprotective, antiproliferative, and anti-inflammatory effects, the anti-inflammatory effects can be explained, at least in part, by reducing neutrophil degranulation, myeloperoxidase activity, mediators as well as TNF-alpha secretion. Isokaempferide is used as a bronchodilator, can induce relaxation of guinea-pig isolated trachea. |
| CFN90644 | Sibiricaxanthone B Sibiricaxanthone B is a natural product from Polygala tenuifolia. |
| CFN90645 | Sibiricose A5 Sibiricose A5 is a lactate dehydrogenase inhibitor, it displays antidepressant-like, and antioxidant actions. Sibiricose A5 can protect PC12 cells damage induced by P. tenuifolia. |
| CFN90646 | Sibiricose A6 Sibiricose A6 displays antidepressant-like action, it may prevent or relieve depression; it also shows potent antioxidant activity. |
| CFN90647 | Calceolarioside B Calceolarioside B has anti-proliferation property. |
| CFN90648 | Astrasieversianin VII Isoastragaloside II is an astragaloside, which is isolated from the hairy root culture of Astragalus membranaceus. |
| CFN90649 | Cimiracemoside D Cimiracemoside D is a narural product from Cimicifuga foetida L. |
| CFN90650 | Polygalasaponin V Polygalasaponin possesses evident anxiolytic and sedative-hypnotic activities and has a relatively safe dose range, which supports the use of Polygala tenuifolia root as an anxiolytic and sedative-hypnotic drug in folk medicine. |
| CFN90651 | Hederagenin 28-O-beta-D-glucopyranosyl ester Reference standards. |
| CFN90652 | Swertiajaponin Swertiajaponin possesses antimicrobial activity. |
| CFN90653 | Orientin 2''-O-p-trans-coumarate Orientin 2''-O-p-trans-coumarate strongly promotes 2BS cell proliferation induced by H(2)O(2). |
| CFN90654 | Vitexin 2''-O-p-coumarate Vitexin 2''-O-p-coumarate strongly promotes 2BS cell proliferation induced by H(2)O(2). |
| CFN90655 | rel-(8R,8'R)-dimethyl-(7S,7'R)-bis(3,4-methylenedioxyphenyl)tetrahydro-furan rel-(8R,8'R)-dimethyl-(7S,7'R)-bis(3,4-methylenedioxyphenyl)tetrahydro-furan is a natural product from Saururus chinensis. |
| CFN90656 | Pseudoginsenoside RT1 Pseudoginsenoside RT1 can cause a decrease in blood pressure, an increase in heart rate and an increase in spontaneous contractility of the uterus. |
| CFN90657 | Esculentoside H Phytolaccaceae has anti-tumor activity, the mechanism may be related to the capacity of Esculentoside H for TNF release. |
| CFN90658 | Esculentoside T |
| CFN90659 | Raddeanoside 20 Raddeanoside 20 can slightly suppress the superoxide generation induced by N-formyl-methionyl-leucyl-phenylalanine (fMLP) in a concentration dependent manner. |
| CFN90660 | 3-Deoxyaconitine 3-Deoxyaconitine has toxicity. |
| CFN90661 | Mudanpioside C Mudanpioside C is a natural product from Paeonia lactiflora Pall. |
| CFN90662 | Benzoyloxypeoniflorin Benzoyloxypeoniflorin contributes to improving blood circulation through their inhibitory effects on both platelet aggregation and blood coagulation. |
