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    Natural Products
    24-Methylenecycloartan-3-ol
    24-Methylenecycloartan-3-ol
    Information
    CAS No. 1449-09-8 Price
    Catalog No.CFN99496Purity>=98%
    Molecular Weight440.8 Type of CompoundTriterpenoids
    FormulaC31H52OPhysical DescriptionPowder
    Download Manual    COA    MSDS    SDFSimilar structuralComparison (Web)  (SDF)
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    According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
    Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
    Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
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    24-Methylenecycloartan-3-ol

    24-Methylenecycloartan-3-ol
    Product Name 24-Methylenecycloartan-3-ol
    CAS No.: 1449-09-8
    Catalog No.: CFN99496
    Molecular Formula: C31H52O
    Molecular Weight: 440.8 g/mol
    Purity: >=98%
    Type of Compound: Triterpenoids
    Physical Desc.: Powder
    Targets: Antifection
    Source: The barks of Larix kaemferi
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
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    Description: 24-Methylenecycloartan-3-ol and methyl caffeate show weak activity against Staphylococcus aureus and Escherichia coli.
    Targets: Antifection
    24-Methylenecycloartan-3-ol Description
    Source: The barks of Larix kaemferi
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 2.2686 mL 11.343 mL 22.686 mL 45.3721 mL 56.7151 mL
    5 mM 0.4537 mL 2.2686 mL 4.5372 mL 9.0744 mL 11.343 mL
    10 mM 0.2269 mL 1.1343 mL 2.2686 mL 4.5372 mL 5.6715 mL
    50 mM 0.0454 mL 0.2269 mL 0.4537 mL 0.9074 mL 1.1343 mL
    100 mM 0.0227 mL 0.1134 mL 0.2269 mL 0.4537 mL 0.5672 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    Protocol
    Structure Identification:
    Lucia Lopes, Jun 10, 2014
    Flavonoids, norisoprenoids and other terpenes from leaves of Tapirira guianensis[Reference: WebLink]

    METHODS AND RESULTS:
    From hexane fraction of methanol extract of leaves of Tapirira guianensis (Anacardiaceae) were obtained lupeol, 24-Methylenecycloartan-3-ol, phytol, α-amyrin, β-amyrin, sitosterol, sitostenone, glycosyl sitosterol, as well as sitosterol esterified with palmitic and stearic acids. Phytol, α-amyrin and β-amyrin esterified with fatty acids were also identified from same extract. The EtOAc extract besides the norisoprenoids (6S,7E,9S)-6,9-dihydroxy-megastigma-4,7-dien -3-one 9-O-β-glucopyranoside and (6S,7E,9R)-6,9-dihydroxy-megastigma-4,7-dien-3-one 9-O-β-glucopyranoside also afforded kaempferol 3-O-rhamnoside, kaempferol 3-O-arabinofuranoside, quercetin 3-O-rhamnoside, and kaempferol.
    CONCLUSIONS:
    The structural elucidation of isolated compounds were based on UV, IR, MS, 1H and 13C NMR data analysis.
    Rev. Bras Farmacogn., 2008, 18(4): 563-8.
    Chemical constituents from leaves of Murraya paniculata (Rutaceae)[Reference: WebLink]

    METHODS AND RESULTS:
    Chromatographic separation of the hexane extract and the CH2Cl2 phase from the ethanol extract from leaves of Murraya paniculata yielded one triterpenoid (24-methylene-cycloartan-3β-ol), one phenylpropanoid (methyl caffeate) and seven coumarins [isomeranzine, murranganone acetate, murrayatine, murrangatine, meranzine hydrate, phebalosine and murranganone].
    CONCLUSIONS:
    All the isolated coumarins were previously obtained from M. paniculata while 24-methylene-cycloartan-3β-ol(24-Methylenecycloartan-3-ol) and methyl caffeate have been described for first time in the Murraya genus. The crude extracts, fractions and pure substances were submitted to evaluation of antimicrobial potential against Staphylococcus aureus and Escherichia coli which indicated that the coumarin meranzine hydrate showed weak activity.
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