Science | Nature | Cell | View More
Natural Products
5,5'-Dimethoxysecoisolariciresinol
5,5'-Dimethoxysecoisolariciresinol
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name 5,5'-Dimethoxysecoisolariciresinol
Price:
CAS No.: 1002106-91-3
Catalog No.: CFN92963
Molecular Formula: C22H30O8
Molecular Weight: 422.47 g/mol
Purity: >=98%
Type of Compound: Lignans
Physical Desc.: Powder
Source: The Heartwoods of Podocarpus spicata
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS
Similar structural: Comparison (Web)  (SDF)
Guestbook:
Contact Us
Order & Inquiry & Tech Support

Tel: (0086)-27-84237683
Tech: service@chemfaces.com
Order: manager@chemfaces.com
Address: 176, CheCheng Eest Rd., WETDZ, Wuhan, Hubei 430056, PRC
How to Order
Orders via your E-mail:

1. Product number / Name / CAS No.
2. Delivery address
3. Ordering/billing address
4. Contact information
Order: manager@chemfaces.com
Delivery time
Delivery & Payment method

1. Usually delivery time: Next day delivery by 9:00 a.m. Order now

2. We accept: Wire transfer & Credit card & Paypal
Citing Use of our Products
* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
Our products had been exported to the following research institutions and universities, And still growing.
  • University of Eastern Finland (Finland)
  • Universidade Federal de Santa C... (Brazil)
  • University of Medicine and Phar... (Romania)
  • Universidade Federal de Pernamb... (Brazil)
  • Yale University (USA)
  • Institute of Chinese Materia Me... (China)
  • Instituto de Investigaciones Ag... (Chile)
  • Universidad Veracuzana (Mexico)
  • Mahatma Gandhi University (India)
  • Sant Gadge Baba Amravati Univer... (India)
  • FORTH-IMBB (Greece)
  • More...
Package
Featured Products
(E)-6-O-(p-coumaroyl)scandoside me...

Catalog No: CFN95192
CAS No: 83946-90-1
Price: $218/10mg
5-Hydroxy-1,7-bis(4-hydroxyphenyl)...

Catalog No: CFN96291
CAS No: 1269839-24-8
Price: $318/10mg
3',4',5'-Trimethoxyflavone

Catalog No: CFN70439
CAS No: 67858-30-4
Price: $118/10mg
21-O-Tigloylgymnemagenin

Catalog No: CFN90978
CAS No: 1581276-63-2
Price: $268/5mg
Forsythoside A

Catalog No: CFN99705
CAS No: 79916-77-1
Price: $50/20mg
Acetyleugenol

Catalog No: CFN70222
CAS No: 93-28-7
Price: $30/20mg
Brazilin

Catalog No: CFN98711
CAS No: 474-07-7
Price: $118/20mg
Wogonoside

Catalog No: CFN99710
CAS No: 51059-44-0
Price: $40/20mg
Cannabidiolic acid

Catalog No: CFN99356
CAS No: 1244-58-2
Price: $413/5mg
Madecassoside

Catalog No: CFN99913
CAS No: 34540-22-2
Price: $40/20mg
Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: 5,5'-Dimethoxysecoisolariciresinol is a natural product from Podocarpus spicata.
In vitro:
Planta Med. 2010 Feb;76(3):294-7.
New secoisolariciresinol derivatives from Lindera obtusiloba stems and their neuroprotective activities.[Pubmed: 19708005 ]

METHODS AND RESULTS:
A methanolic extract of Lindera obtusiloba (Lauraceae) stems significantly attenuated glutamate-induced oxidative stress in HT22 hippocampal cells. Two new secoisolariciresinol derivatives, characterized as 9,9'- O-di-(E)-feruloyl-meso-5,5'-Dimethoxysecoisolariciresinol (1) and 9,9'-O-di-(E)-sinapinoyl-meso-5,5'-Dimethoxysecoisolariciresinol (2), were isolated, along with the known compound 9,9'-O-di-(E)-feruloyl-meso-secoisolariciresinol (3), from the methanolic extract of L. obtusiloba stems.
CONCLUSIONS:
Compounds 1, 2, and 3 showed neuroprotective effects on glutamate-induced toxicity in HT22 cells.
5,5'-Dimethoxysecoisolariciresinol Description
Source: The Heartwoods of Podocarpus spicata
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
ChemFaces New Products and Compounds
Physalin X

Catalog No: CFN95329
CAS No: 72497-31-5
Price: $318/5mg
Toddalolactone 3'-O-methyl ether (...

Catalog No: CFN95372
CAS No: 143614-35-1
Price: $318/10mg
Planispine A

Catalog No: CFN95348
CAS No: 1202761-42-9
Price: $318/10mg
Leachianol G

Catalog No: CFN95146
CAS No: 164204-62-0
Price: $368/5mg
New compound 5

Catalog No: CFN95258
CAS No: N/A
Price: $413/5mg
Arvenin III

Catalog No: CFN95327
CAS No: 65597-45-7
Price: $318/5mg
Lucidenic acid D2

Catalog No: CFN95020
CAS No: 98665-16-8
Price: $268/5mg
Alopecurone A

Catalog No: CFN95512
CAS No: 162558-89-6
Price: $318/10mg
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.367 mL 11.8352 mL 23.6703 mL 47.3406 mL 59.1758 mL
5 mM 0.4734 mL 2.367 mL 4.7341 mL 9.4681 mL 11.8352 mL
10 mM 0.2367 mL 1.1835 mL 2.367 mL 4.7341 mL 5.9176 mL
50 mM 0.0473 mL 0.2367 mL 0.4734 mL 0.9468 mL 1.1835 mL
100 mM 0.0237 mL 0.1184 mL 0.2367 mL 0.4734 mL 0.5918 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Zhong Yao Cai. 2015 May;38(5):972-4.
Chemical Constitutes from Root of Artocarpus styracifolius.[Pubmed: 26767289]
To study the chemical constituents from root of Artocarpus styracifolius.
METHODS AND RESULTS:
Tne constituents were isolated from the root of Artocarpus styracifolius by column chromatography over silica gel, RP-18 silica gel, MCI GEL CHP-20P, macroporous resin HP-20, Sephadex LH-20, Toyopearl HW-40C and by preparative HPLC. Their structures were elucidated by analysis of physical and chemical properties and spectral data. RESULTS: Nine compounds were isolated and their structures were identified as p-hydroxy benzoic acid (1), syringic acid (2), 2,4-dihydroxy benzaldehyde (3), (+)-lyoniresinol (4), 5,5'-Dimethoxysecoisolariciresinol (5), (+)- syringaresinol (6), scopoletin (7), xylarolide (8) and trans-oxyresveratrol (9).
CONCLUSIONS:
Compounds 2, 5, 6 and 8 are isolated from Moraceae for the first time. Compounds 1, 4 and 7 are firstly characterized in the genus Artocarpus, compounds 3 and 9 are characterized in Artocarpus styracifolius for the first time.
(E)-6-O-(p-coumaroyl)scandoside me...

Catalog No: CFN95192
CAS No: 83946-90-1
Price: $218/10mg
5-Hydroxy-1,7-bis(4-hydroxyphenyl)...

Catalog No: CFN96291
CAS No: 1269839-24-8
Price: $318/10mg
3',4',5'-Trimethoxyflavone

Catalog No: CFN70439
CAS No: 67858-30-4
Price: $118/10mg
21-O-Tigloylgymnemagenin

Catalog No: CFN90978
CAS No: 1581276-63-2
Price: $268/5mg
Forsythoside A

Catalog No: CFN99705
CAS No: 79916-77-1
Price: $50/20mg
Acetyleugenol

Catalog No: CFN70222
CAS No: 93-28-7
Price: $30/20mg
Brazilin

Catalog No: CFN98711
CAS No: 474-07-7
Price: $118/20mg
Wogonoside

Catalog No: CFN99710
CAS No: 51059-44-0
Price: $40/20mg
Cannabidiolic acid

Catalog No: CFN99356
CAS No: 1244-58-2
Price: $413/5mg
Madecassoside

Catalog No: CFN99913
CAS No: 34540-22-2
Price: $40/20mg
Tags: buy 5,5'-Dimethoxysecoisolariciresinol | 5,5'-Dimethoxysecoisolariciresinol supplier | purchase 5,5'-Dimethoxysecoisolariciresinol | 5,5'-Dimethoxysecoisolariciresinol cost | 5,5'-Dimethoxysecoisolariciresinol manufacturer | order 5,5'-Dimethoxysecoisolariciresinol | 5,5'-Dimethoxysecoisolariciresinol distributor