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    Natural Products
    Homobaldrinal
    Information
    CAS No. 67910-07-0 Price
    Catalog No.CFN90540Purity>=98%
    Molecular Weight260.28Type of CompoundIridoids
    FormulaC15H16O4Physical DescriptionPowder
    Download Manual    COA    MSDS    SDFSimilar structuralComparison (Web)  (SDF)
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    According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
    Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
    Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
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    Homobaldrinal

    Homobaldrinal
    Product Name Homobaldrinal
    CAS No.: 67910-07-0
    Catalog No.: CFN90540
    Molecular Formula: C15H16O4
    Molecular Weight: 260.28 g/mol
    Purity: >=98%
    Type of Compound: Iridoids
    Physical Desc.: Powder
    Source: The herbs of Valeriana officinalis L.
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
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    Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
    10 mM * 1 mL in DMSO / Inquiry / In-stock
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  • Biological Activity
    Description: Homobaldrinal has low toxic activity. It has genotoxic activity in the Salmonella/microsome test and the SOS-chromotest.
    In vitro:
    Mutat Res. 1986 Jan-Feb;169(1-2):23-7.
    Bacterial mutagenicity of the tranquilizing constituents of Valerianaceae roots.[Pubmed: 3511364 ]
    The valepotriates valtrate/isovaltrate and dihydrovaltrate are considered to be the main tranquilizing constituents of drugs derived from the roots of several Valerianaceae.
    METHODS AND RESULTS:
    The decomposition products of valtrate and isovaltrate include the metabolites baldrinal and Homobaldrinal, respectively, whereas the decomposition products of dihydrovaltrate do not include baldrinal-like metabolites. Purified valtrate/isovaltrate, dihydrovaltrate, baldrinal and Homobaldrinal were investigated for their genotoxic activity in the Salmonella/microsome test and the SOS-chromotest.
    CONCLUSIONS:
    The valepotriates developed mutagenic activity in these test systems only in the presence of S9 mix, whereas both baldrinals showed mutagenic effects in both tests with and without metabolic activation.
    Phytomedicine. 1998 May;5(3):219-25.
    Cytotoxic potential of valerian constituents and valerian tinctures.[Pubmed: 23195845]

    METHODS AND RESULTS:
    The monoene type valepotriates (didrovaltrate and isovaleroxyhydroxydidrovaltrate) were 2- to 3-fold less toxic. Baldrinal and Homobaldrinal, decomposition products of valepotriates, were 10- to 30-fold less toxic than their parent compounds.
    Homobaldrinal Description
    Source: The herbs of Valeriana officinalis L.
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 3.842 mL 19.2101 mL 38.4202 mL 76.8403 mL 96.0504 mL
    5 mM 0.7684 mL 3.842 mL 7.684 mL 15.3681 mL 19.2101 mL
    10 mM 0.3842 mL 1.921 mL 3.842 mL 7.684 mL 9.605 mL
    50 mM 0.0768 mL 0.3842 mL 0.7684 mL 1.5368 mL 1.921 mL
    100 mM 0.0384 mL 0.1921 mL 0.3842 mL 0.7684 mL 0.9605 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
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