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(-)-Lyoniresinol
(-)-Lyoniresinol
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name (-)-Lyoniresinol
Price:
CAS No.: 31768-94-2
Catalog No.: CFN92578
Molecular Formula: C22H28O8
Molecular Weight: 420.5 g/mol
Purity: >=98%
Type of Compound: Lignans
Physical Desc.: Cryst.
Source: The root barks of Berberis vulgaris
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF    Manual
Similar structural: Comparison (Web)  (SDF)
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
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Product Use Citation
Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: (-)-Lyoniresinol has antioxidant activity.
In vitro:
Chemistry & Biodiversity 6(4):540-50.
arennanosides A-H, Eight New Lignan Glucosides from Tarenna attenuata and Their Protective Effect on H 2 O 2 -Induced Impairment in PC12 Cells.[Reference: WebLink]

METHODS AND RESULTS:
Eight new lignan glucosides, tarennanosides A-H ( 1 - 8 , resp.), were isolated from the whole plant of Tarenna attenuata , together with three known compounds, fernandoside, (-)-Lyoniresinol, and (-) - isolariciresinol. The planar structures of new compounds were elucidated mainly by analysis of physical and spectroscopic data, and the absolute configurations were determined by acid hydrolysis as well as CD spectroscopy. Compounds 1 and 2 exhibited potent antioxidant activities against H2O2-induced impairment in PC12 cells.
CONCLUSIONS:
Preliminary mechanism study by the 1,1-diphenyl-2-picrylhydrazyl (DPPH) method showed that these two compounds could act as radical scavengers.
(-)-Lyoniresinol Description
Source: The root barks of Berberis vulgaris
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
More...

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

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Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.3781 mL 11.8906 mL 23.7812 mL 47.5624 mL 59.453 mL
5 mM 0.4756 mL 2.3781 mL 4.7562 mL 9.5125 mL 11.8906 mL
10 mM 0.2378 mL 1.1891 mL 2.3781 mL 4.7562 mL 5.9453 mL
50 mM 0.0476 mL 0.2378 mL 0.4756 mL 0.9512 mL 1.1891 mL
100 mM 0.0238 mL 0.1189 mL 0.2378 mL 0.4756 mL 0.5945 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Journal of Natural Products, 2004, 52(6):1327-1330.
Lignan Glycosides from the Heartwood of European Oak Quercus petraea.[Reference: WebLink]

METHODS AND RESULTS:
( + )-Lyoniresinol [1] and (-)-Lyoniresinol [ent-1] (the former being more abundant), (+)-lyoniresinol 2a-O-β-D-glucopyranoside [3], lyoniside [4], and a new metabolite, namely (-)-Lyoniresinol 2a-O-β-D-xylopyranoside (ent-4) 1, have been isolated from Quercus petraea heartwood.
CONCLUSIONS:
Their structures were deduced from chemical and spectral data. 1 The term ent refers to the aglycone moiety.
CFN92070Isolintetralin145459-30-9400.5C23H28O6
CFN92852Nirtetralin78185-63-4430.5C24H30O7
CFN98431Hypophyllanthin33676-00-5430.5 C24H30O7
CFN92578(-)-Lyoniresinol31768-94-2420.5C22H28O8
CFN967105-Methoxyisolariciresinol136082-41-2390.43C21H26O7
CFN96566Spathulatol1373888-27-7538.59C30H34O9
CFN95480Cagayanin99096-51-2714.9C42H50O10
CFN97039Guaiacin36531-08-5328.4 C20H24O4
CFN99005Wulignan A1117047-76-4342.4C20H22O5
CFN95211Arisantetralone B1161947-96-1342.4C20H22O5
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