Neoquassine | CAS:76-77-7 | Manufacturer ChemFaces

Neoquassine

ChemFaces products have been cited in many studies from excellent and top scientific journals

Product Name	Neoquassine
Price:	$218 / 5mg
CAS No.:	76-77-7
Catalog No.:	CFN92142
Molecular Formula:	C₂₂H₃₀O₆
Molecular Weight:	390.5 g/mol
Purity:	>=98%
Type of Compound:	Diterpenoids
Physical Desc.:	Cryst.
Source:	The barks of Ailanthus altissima (Mill.) Swingle
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS SDF Manual
Similar structural:	Comparison (Web) (SDF)
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* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.

According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.

Size /Price /Stock	10 mM * 1 mL in DMSO / $185.3 / In-stock
Other Packaging	*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap

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Neoquassine Description

Source:	The barks of Ailanthus altissima (Mill.) Swingle
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Structure Identification:

J. Agric. Food Chem.,2010, 58(5):2807-11.

Liquid chromatography electrospray ionization tandem mass spectrometric determination of quassin and neoquassin in fruits and vegetables.[Pubmed: 20196620]

Quassia amara wood chips are used by organic farmers as a valid alternative to synthetic insecticides. The powder of Q. amara contains high levels of quassin, neoquassin and picrasinoside B. In this study we developed a liquid chromatography mass spectrometry method for the rapid and accurate quantification of the insecticide quassinoids on fruits and vegetables.
METHODS AND RESULTS:
Quassinoids were extracted from fruits and vegetables with acetonitrile and separated on a Zorbax Column Eclipse XDB C8 by isocratic elution with a mobile phase consisting of water and methanol with 0.1% of formic acid. Using a high-performance liquid chromatograph coupled with an electrospray ionization tandem mass spectrometer (HPLC/ESI-MS/MS), quassinoids were selectively and simultaneously detected monitoring the multiple reaction (MRM) transitions of proton adduct precursor ions: m/z 389.5 --> 222.9 for quassin, 391.5 --> 372.9 for neoquassin and 576.1 --> 394.5 for picrasinoside B. For all quassinoids calibration was linear over a working range of 1 and 100 microg/kg with r > 0.991. Limit of determination (LOD) and limit of quantification (LOQ) for both quassinoids were 0.5 and 1 microg/kg respectively while for picrasinoside B they were 5 and 10 microg/kg. Quassinoid recoveries ranged from 85.3% to 105.3% with coefficients of variation between 2.5% and 12.8% for fruit and vegetables. The presence of interfering compounds in the fruit and vegetable extract was evaluated and found to be minimal.
CONCLUSIONS:
Due to the linear behavior it was concluded that the multiple reaction transitions of precursor ions can be used for analytical purposes, i.e. for identification and quantification of quassin, neoquassin(Neoquassine), and picrasinoside B in fruit and vegetable extracts at trace levels.

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Insecticides Compound Library Diterpenoids Compound Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	2.5608 mL	12.8041 mL	25.6082 mL	51.2164 mL	64.0205 mL
5 mM	0.5122 mL	2.5608 mL	5.1216 mL	10.2433 mL	12.8041 mL
10 mM	0.2561 mL	1.2804 mL	2.5608 mL	5.1216 mL	6.402 mL
50 mM	0.0512 mL	0.2561 mL	0.5122 mL	1.0243 mL	1.2804 mL
100 mM	0.0256 mL	0.128 mL	0.2561 mL	0.5122 mL	0.6402 mL

CFN92981	Shinjulactone L	4283-49-2	406.47	C₂₂H₃₀O₇
CFN92142	Neoquassine	76-77-7	390.5	C₂₂H₃₀O₆
CFN92143	Methylneoquassin	89498-93-1	404.5	C₂₃H₃₂O₆
CFN97246	Quassin	76-78-8	388.5	C₂₂H₂₈O₆
CFN89342	Dehydrobruceantinol	99132-99-7	604.59	C₃₀H₃₆O₁₃
CFN89343	Bruceantinoside A	79439-85-3	710.71	C₃₄H₄₆O₁₆
CFN96423	Yadanzioside F	95258-11-0	642.60	C₂₉H₃₈O₁₆
CFN95080	Bruceoside A	63306-30-9	682.7	C₃₂H₄₂O₁₆
CFN96425	Yadanzioside A	95258-15-4	684.68	C₃₂H₄₄O₁₆
CFN96424	Yadanzioside C	95258-16-5	726.72	C₃₄H₄₆O₁₇