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    Natural Products
    Quercetagetin-7-O-glucoside
    Information
    CAS No. 548-75-4 Price $388 / 10mg
    Catalog No.CFN90855Purity>=98%
    Molecular Weight480.4Type of CompoundFlavonoids
    FormulaC21H20O13Physical DescriptionYellow powder
    Download     COA    MSDS    SDFSimilar structuralComparison (Web)  (SDF)
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    According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
    Size /Price /Stock 10 mM * 1 mL in DMSO / $252.2 / In-stock
    Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
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    Quercetagetin-7-O-glucoside

    Quercetagetin-7-O-glucoside
    Product Name Quercetagetin-7-O-glucoside
    CAS No.: 548-75-4
    Catalog No.: CFN90855
    Molecular Formula: C21H20O13
    Molecular Weight: 480.4 g/mol
    Purity: >=98%
    Type of Compound: Flavonoids
    Physical Desc.: Yellow powder
    Targets: Immunology & Inflammation related
    Source: The herbs of Tagetes erecta L.
    Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
    Price: $388 / 10mg
    Inquire / Order: manager@chemfaces.com
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  • Related Screening Libraries
    Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
    10 mM * 1 mL in DMSO / Inquiry / In-stock
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  • Biological Activity
    Description: Quercetagetin-7-O-glucoside, a potent inhibitor of beta-glucuronidase and lysozyme release, shows anti-inflammatory activity, can significantly inhibit arachidonic acid release from membranes.
    Targets: Immunology & Inflammation related
    In vitro:
    Z Naturforsch C. 1994 Mar-Apr;49(3-4):235-40.
    Influence of anti-inflammatory flavonoids on degranulation and arachidonic acid release in rat neutrophils.[Pubmed: 8018254]
    We assessed the effects of 24 flavonoid derivatives, reported as anti-inflammatory, on lysosomal enzyme secretion and arachidonic acid release in rat neutrophils.
    METHODS AND RESULTS:
    Amentoflavone, Quercetagetin-7-O-glucoside, apigenin, fisetin, kaempferol, luteolin and quercetin were the most potent inhibitors of beta-glucuronidase and lysozyme release. The first compound was also able to inhibit basal release. These flavonoids besides chrysin and to a reduced extent, naringenin, significantly inhibited arachidonic acid release from membranes.
    CONCLUSIONS:
    A correlation between degranulation and arachidonic acid release was found for this series of compounds. Structure-activity relationships and implications for the anti-inflammatory effects of these flavonoids were discussed.
    Quercetagetin-7-O-glucoside Description
    Source: The herbs of Tagetes erecta L.
    Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Cell. 2018 Jan 11;172(1-2):249-261.e12.
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    IF=36.216(2019)

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    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 2.0816 mL 10.408 mL 20.816 mL 41.632 mL 52.04 mL
    5 mM 0.4163 mL 2.0816 mL 4.1632 mL 8.3264 mL 10.408 mL
    10 mM 0.2082 mL 1.0408 mL 2.0816 mL 4.1632 mL 5.204 mL
    50 mM 0.0416 mL 0.2082 mL 0.4163 mL 0.8326 mL 1.0408 mL
    100 mM 0.0208 mL 0.1041 mL 0.2082 mL 0.4163 mL 0.5204 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    Protocol
    Structure Identification:
    Nat Prod Commun. 2015 Mar;10(3):447-50.
    Anthocyanins and other flavonoids as flower pigments from eleven Centaurea species.[Pubmed: 25924526]
    Anthocyanins and other flavonoids were isolated from the flowers of eleven Centaurea species, C. macrocephala, C. rupestotilis and C. suaveolens, which produce yellow flowers, and C. achtarovii, C. dealbata, C. montana, C. nigra, C. scabiosa, C. simplicicaulis, C. hypoleuca and C. triumfetti, which have cyanic flowers. Four anthocyanins, cyanidin 3,5-di-O-glucoside, cyanidin 3-O-(6"-malonylglucoside)-5-O-glucoside, cyanidin 3-O-(6"-succinylglucoside)-5- O-glucoside and cyanidin glycoside, were detected in the cyanic flowers of seven Centaurea species.
    METHODS AND RESULTS:
    Of these anthocyanins, the first two were found as major anthocyanins. In the cyanic species, four other flavonoids, apigenin 7-O-glucuronide-4'-O-glucoside, malonylated apigenin 7,4'-di-O-glucoside, apigenin 7-0- glucuronide and kaempferol glycoside, were also isolated. On the other hand, nine flavonols and four flavones were isolated from the three yellow-flowered species, and identified as quercetagetin, Quercetagetin-7-O-glucoside, quercetagetin 3'-methyl ether 7-O-glucoside, patuletin, patuletin 7-O-glucoside, quercetin 7-O-glucoside, kaempferol 3-methyl ether, kaempferol 3-methyl ether 4'-O-glucuronide and isorhamnetin 3-O-galactoside, and apigenin, apigenin 7- O-glucuronide, luteolin 7-O-glucoside and apigenin 6,8-di-C-glucoside (vicenin-2).
    CONCLUSIONS:
    Of these flavonoids, the former five flavonols are "yellow flavonols", and it was shown that their flower colors are due to these compounds.
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