Natural Products
| Catalog No. | Information |
| CFN96241 | Demethylsuberosin Demethylsuberosin has potential anti-inflammatory activity, it displays suppressive effects on LPS-induced NO and PGE2 production with the IC50 value of 9.42 uM. |
| CFN96242 | Akuammidine Akuammidine shows anti-inflammatory and anti-asthmatic properties, it has opioid analgesic activity, it shows a preference for mu-opioid binding sites with Ki values of 0.6, 2.4 and 8.6 microM at mu-, delta- and kappa-opioid binding sites, respectively. |
| CFN96243 | 10-Hydroxyneoline 10-Hydroxyneoline is a natural product from Aconitum fukutomei. |
| CFN96244 | Megastigm-7-ene-3,4,6,9-tetrol Megastigm-7-ene-3,4,6,9-tetrol is a natural product from Apollonias barbujana. |
| CFN96245 | Fargesone A Fargesone A shows inhibitory effects on nitric oxide (NO) production in the lipopolysaccharide plus interferon-gamma activated-murine macrophage cell line, J774.1. |
| CFN96246 | 2'',4''-Di-O-(E-p-coumaroyl)afzelin Antimicrobial agent. |
| CFN96247 | Pterolactone A Reference standards. |
| CFN96248 | Hannokinol (+)-Hannokinol and MESO-hannokinol can significantly inhibit lipopolysaccharide-induced nitric oxide production in BV2 microglial cells at concentrations ranging from 1 microM to 100 microM. |
| CFN96249 | Futoquinol Futoquinol is an anti-platelet activating factor principle from the stem part of Piper futokadsura (Piperaceae), the Chinese drug haifengteng. Futoquinol has anti-neuroinflammatory activity, it can potently inhibit NO production with an IC(50) value of 16.8 microM in microglia cells. Futoquinol shows potent inhibition of PMA-induced ROS production in human polymorphonuclear neutrophils with IC(50) values 13.1 +/- 5.3 microM. |
| CFN96250 | Kadsurin A Kadsurin A and Kadsurin B have anti-platelet activating factor activities. |
| CFN96251 | Bis-5,5-nortrachelogenin Bis-5,5-nortrachelogenin has anti-allergic activity, it inhibited NO production with IC50 value of 48.6 microM. |
| CFN96252 | Protosappanin A dimethyl acetal Protosappanin A dimethyl acetal shows significant xanthine oxidase inhibitory activity in a concentration-dependent manner. |
| CFN96253 | Mulberrofuran G pentaacetate Reference standards. |
| CFN96254 | Dammarenediol II 3-O-caffeate Dammarenediol II 3-O-caffeate is a natural product from Ostryopsis nobilis. |
| CFN96255 | Lupeolic acid Lupeolic acid has anti-inflammatory activity. |
| CFN96256 | Glycosolone Glycosolone shows some toxicity on mosquito larvae (Culex quinquefasciatus). |
| CFN96257 | Denudanolide A Reference standards. |
| CFN90859 | Notoginsenoside Ft1 Notoginsenoside Ft1 is a novel stimulator of angiogenesis, it stimulates angiogenesis via HIF-1α-mediated VEGF expression, with PI3K/AKT and Raf/MEK/ERK signaling cascades concurrently participating in the process; it has the potential therapeutic effect on human neuroblastoma, it can arrest the proliferation and elicited the apoptosis of SH-SY5Y cells possibly via p38 MAPK and ERK1/2 pathways.Notoginsenoside Ft1 activates both glucocorticoid and estrogen receptors to induce endothelium-dependent, nitric oxide-mediated relaxations in rat mesenteric arteries. Notoginsenoside Ft1 also provides a great potential application of it in clinics for patients with diabetic foot ulcers, it may accelerate diabetic wound healing by orchestrating multiple processes, including promoting fibroblast proliferation, enhancing angiogenesis, and attenuating inflammatory response. |
| CFN93254 | Lysicamine Lysicamine shows significant antioxidant capacity in the ORAC(FL) assay and it is active against S. epidermidis and C. dubliniensis, with MIC values in the range 12.5-100 microg mL(-1). Lysicamine has antimicrobial and anti-inflammation activity, the minimum inhibitory concentrations of the pour component (Streptococcus mutans, Porphyromonas gingivalis, Actinobacillus actinomycetemcomitans and Candida albicans.) is less than 5mg/ml for all four microorganisms and the minimum concentration with anti-inflammation is 0.2mg/ml for both IL-8 and IL-6. Lysicamine has antileishmanial activity. It can significantly inhibit the proliferation of melanoma cells, it has antioxidative activity and chemopreventive activity in skin melanoma cells. |
| CFN94151 | Cepharadione B Cepharadione B exhibits strong tyrosinase inhibitory activity with an IC50 value of 170 microM. It also exhibits significant cytotoxicity against five human tumor cell lines (A-549, SK-OV-3, SK-MEL-2, XF-498 and HCT-15) in vitro. |
| CFN90860 | beta-Cyclodextrin methyl ethers |
| CFN90861 | Continentalic acid Continentalic acid and kaurenoic acid are quality control markers in Aralia continentalis. Continentalic acid has anti-inflammatory, anti-cancer, and anti-bacterial activities, it shows moderate cytotoxicity against A-549 (lung), THP-1 (leukemia) and MCF-7 (breast) cell lines; it has minimum inhibitory concentrations (MICs) of approximately 8-16 microg/mL against S. aureus, including the MSSA and MRSA standard strains. |
| CFN90862 | Perillen Perillen is a nartural product from Perilla frutescens. |
| CFN90863 | Cimicidanol 3-O-alpha-L-arabinoside Reference standards. |
| CFN90864 | meso-Hannokinol meso-Hannokinol and (+)-hannokinol can significantly inhibit lipopolysaccharide-induced nitric oxide production in BV2 microglial cells at concentrations ranging from 1 uM to 100 uM. |
| CFN90865 | Beta-D-glucopyranosyl oleanolate Beta-D-glucopyranosyl oleanolate is a natural product from Hedera nepalensis. |
| CFN90866 | N-Benzyllinolenamide Reference standards. |
| CFN90867 | Neoisoastilbin Neoisoastilbin may have antioxidant and anti-inflammatory activities. |
| CFN90868 | Picroside IV Kutkoside is a mixture of iridoid glycosides namely, picroside II, Picroside IV and 6-ferulloylcatalpol, it may have antinociceptive and anti-inflammatory effects. |
| CFN94481 | 2,3-Dihydroxy-4-methoxybenzoic acid Reference standards. |
| CFN94461 | 2-Hydroxy-3,4-dimethoxybenzoic acid |
| CFN94403 | 4-Methoxycoumarine 4-Methoxycoumarin has antitumour effects. |
| CFN94425 | 6-Methoxy-4-methylcoumarin 6-Methoxy-4-methylcoumarin is a natural product from Eupatorium pauciflorum. |
| CFN94465 | 7,8-Benzoflavone 7,8-Benzoflavone is one of the most potent inhibitors of breast cancer resistance protein (BCRP). |
| CFN94487 | 7-Hydroxyflavanone 7-Hydroxyflavanone shows antimicrobial activity against Streptococcus pneumoniae clinical isolates, it could be useful for the development of a novel respiratory infections treatment. |
| CFN94405 | 7-Methoxy-4-methylcoumarin 7-Methoxy-4-methylcoumarin is a coumarin derivative and fluorescent label, it displays good activity against B. subtilis. |
| CFN94408 | Carminic acid Carminic acid, the well-known red dyestuff from cochineal insects (Dactylopius spp.), is a potent feeding deterrent to ants. Carminic acid is an antioxidant to protect erythrocytes and DNA against radical‐induced oxidation, it also has antitumor activity. |
| CFN94482 | Dihydrosinapylalcohol Dihydrosinapylalcohol is a natural product from Clerodendranthus spicatus. |
| CFN94478 | Kojic acid Kojic acid has been used as a food additive for preventing enzymatic browning of crustaceans and as a cosmetic agent for skin whitening. Kojic acid exhibits concentration-dependent scavenging activity on DPPH possessing strong antioxidant activity, it can reduce the mortality induced by gamma irradiation; it exhibits a competitive inhibition for the oxidation of chlorogenic acid and catechol by potato polyphenol oxidase (PPO) and of 4-methylcatechol and chlorogenic acid by apple PPO; it also has significant tyrosinase inhibitory activity. |
| CFN94455 | Lanatoside B Lanatoside B is a natural product from Polygonum lapathifolium. |
| CFN94479 | Procaine Procaine is a benzoic acid derivative with local anesthetic and antiarrhythmic properties. Procaine binds to and inhibits voltage-gated sodium channels, thereby inhibiting the ionic flux required for the initiation and conduction of impulses. It is a DNA-demethylating agent with growth-inhibitory effects in human cancer cells, it inhibits the Wnt canonical pathway by promoter demethylation of WIF-1 in lung cancer cells. |
| CFN94466 | Quercetin-3-O-glucose-6''-acetate Quercetin-3-O-glucose-6''-acetate is a NADPH oxidase inhibitor, it has antioxidant capacity. |
| CFN94427 | Vulpic acid Vulpic acid has therapeutic and prophylactic potential to be antibacterial and antiplasmodial agents, it can inhibit one or more enzymes (PfFabI, PfFabG, and PfFabZ) from the plasmodial fatty acid biosynthesis (FAS-II) pathway, a potential drug target for liver stage activity. |
| CFN94111 | Chelidonic acid Chelidonic acid is a component of Chelidonium majus L., used as a mild analgesic, an antimicrobial, an acentral nervous system sedative. Chelidonic acid also shows anti-inflammatory activity. Chelidonic acid has potential to inhibit IL-6 production by blocking NF-κB and caspase-1. Chelidonic acid is a glutamate decarboxylase inhibitor, with a Ki of 1.2 μM. |
| CFN94213 | 4'-Hydroxyflavanone 4'-Hydroxyflavanone may have major potential as a pharmaceutical preparation against hepatic steatosis and dyslipidemia. 4'-Hydroxyflavanone shows full vasorelaxing effects; it also shows inhibition of nitric oxide production in lipopolysaccharide (LPS)-stimulated product of nitrite in RAW 264.7 cells with the IC50 value of 15.72 ug/mL. |
| CFN95007 | 8,8''-Bibaicalein 8,8''-Bibaicalein is a natural product from Scutellaria baicalensis. |
| CFN95008 | Isonemerosin Reference standards. |
| CFN94818 | Aescin IIA Reference standards. |
| CFN94827 | Dipsacobioside Dipsacobioside is a natural product from Dipsacus azureus Schrenk. |
| CFN94808 | Hederacolchiside A1 Hederacolchiside A1 shows anti-leishmanial activity, it exhibits a strong antiproliferative activity on all stages of development of the parasite by altering membrane integrity and potential. Hederacolchiside A1 shows antiproliferation activities in three cancer cell lines with the IC50 value of 2.4 uM, it exhibits a preferential cytotoxicity on a pigmented melanoma cell line. |
