Science | Nature | Cell | View More
Natural Products
Isovallesiachotamine
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Isovallesiachotamine
Price:
CAS No.: 34384-71-9
Catalog No.: CFN92641
Molecular Formula: C21H22N2O3
Molecular Weight: 350.4 g/mol
Purity: >=98%
Type of Compound: Alkaloids
Physical Desc.: Powder
Source: The seeds of Strychnos nux-vomica Linn.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF
Similar structural: Comparison (Web)  (SDF)
Guestbook:
Contact Us
Order & Inquiry & Tech Support

Tel: (0086)-27-84237683
Tech: service@chemfaces.com
Order: manager@chemfaces.com
Address: 176, CheCheng Eest Rd., WETDZ, Wuhan, Hubei 430056, PRC
How to Order
Orders via your E-mail:

1. Product number / Name / CAS No.
2. Delivery address
3. Ordering/billing address
4. Contact information
Order: manager@chemfaces.com
Delivery time
Delivery & Payment method

1. Usually delivery time: Next day delivery by 9:00 a.m. Order now

2. We accept: Wire transfer & Credit card & Paypal
Citing Use of our Products
* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
Our products had been exported to the following research institutions and universities, And still growing.
  • Biotech R&D Institute (USA)
  • Uniwersytet Medyczny w ?odzi (Poland)
  • Northeast Normal University Cha... (China)
  • Cornell University (USA)
  • National Cancer Center Research... (Japan)
  • Monash University Malaysia (Malaysia)
  • Sanford Burnham Prebys Medical ... (USA)
  • University of Virginia (USA)
  • University of Leipzig (Germany)
  • Washington State University (USA)
  • Universidad Veracuzana (Mexico)
  • More...
Package
Featured Products
Isobavachin

Catalog No: CFN98400
CAS No: 31524-62-6
Price: $138/20mg
Taurocholic acid

Catalog No: CFN96646
CAS No: 81-24-3
Price: $ / mg
Dehydroglyasperin C

Catalog No: CFN96483
CAS No: 199331-35-6
Price: $ / mg
2''-O-Rhamnosylicariside II

Catalog No: CFN92551
CAS No: 135293-13-9
Price: $288/10mg
Oxoglaucine

Catalog No: CFN90508
CAS No: 5574-24-3
Price: $318/5mg
Lobetyolin

Catalog No: CFN99104
CAS No: 136085-37-5
Price: $168/20mg
Corynoxeine

Catalog No: CFN98154
CAS No: 630-94-4
Price: $148/20mg
Conduritol A

Catalog No: CFN98868
CAS No: 526-87-4
Price: $258/10mg
N-trans-caffeoyltyramine

Catalog No: CFN95265
CAS No: 103188-48-3
Price: $318/5mg
Kaempferol 3-neohesperidoside

Catalog No: CFN98415
CAS No: 32602-81-6
Price: $/mg
Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Standard reference
In vitro:
Planta Med. 1982 May;45(5):28-30.
Vallesiachotamine and isovallesiachotamine from the seeds of Strychnos tricalysioides.[Pubmed: 17396774]

METHODS AND RESULTS:
A new indole alkaloid, 11-hydroxypolyneuridine, was isolated from Vinca major subsp. major L. and the known indole alkaloids vallesiachotamine and Isovallesiachotamine from Vinca minor L. This is the first report on the alkaloids of both Vinca species growing in Turkey; vallesiachotamine and Isovallesiachotamine were isolated from a Vinca species for the first time. V. minor may be considered as a new source for these two alkaloids due to their occurrence in high amount in the aerial parts of the plant.
CONCLUSIONS:
The alkaloid extracts of the two Vinca species were found to have high lipid peroxidation inhibitory and DPPH radical scavenging activities. Anticholinesterase activity of the extracts was also very strong.
J Nat Prod. 2003 Jul;66(7):1017-21.
Turbinatine, a potential key intermediate in the biosynthesis of corynanthean-type indole alkaloids.[Pubmed: 12880329]

METHODS AND RESULTS:
Extraction of the leaves of Chimarrhis turbinata has led to the isolation of turbinatine (1), a new corynanthean-type indole alkaloid, besides four known indole alkaloids, strictosidine, 5alpha-carboxystrictosidine, vallesiachotamine, and Isovallesiachotamine. The structural determination of 1 was based on 1D and 2D spectroscopic data.
CONCLUSIONS:
An evaluation of the DNA-damaging activities of the isolates was performed by means of a bioassay using mutant strains of Saccharomyces cerevisiae, which indicated these compounds were weakly active.
Isovallesiachotamine Description
Source: The seeds of Strychnos nux-vomica Linn.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
ChemFaces New Products and Compounds
2-Phenylethyl-beta-glucopyranoside

Catalog No: CFN95429
CAS No: 18997-54-1
Price: $318/10mg
12beta-Acetoxy-3,7,11,15,23-pentao...

Catalog No: CFN95505
CAS No: 1309931-91-6
Price: $318/5mg
Citrusin B

Catalog No: CFN95178
CAS No: 105279-10-5
Price: $388/5mg
Erythro-Guaiacylglycerol-beta-coni...

Catalog No: CFN95416
CAS No: 74474-55-8
Price: $318/5mg
Physalin G

Catalog No: CFN95104
CAS No: 76045-38-0
Price: $388/5mg
Astin C

Catalog No: CFN95189
CAS No: 148057-23-2
Price: $318/10mg
Isoeuphorbetin

Catalog No: CFN95207
CAS No: 50677-55-9
Price: $318/5mg
New compound 12 (Rhoifolin analog)

Catalog No: CFN95371
CAS No: N/A
Price: $318/5mg
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.8539 mL 14.2694 mL 28.5388 mL 57.0776 mL 71.347 mL
5 mM 0.5708 mL 2.8539 mL 5.7078 mL 11.4155 mL 14.2694 mL
10 mM 0.2854 mL 1.4269 mL 2.8539 mL 5.7078 mL 7.1347 mL
50 mM 0.0571 mL 0.2854 mL 0.5708 mL 1.1416 mL 1.4269 mL
100 mM 0.0285 mL 0.1427 mL 0.2854 mL 0.5708 mL 0.7135 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Nat Prod Commun. 2012 Jun;7(6):731-4.
Indole alkaloids from Vinca major and V. minor growing in Turkey.[Pubmed: 22816294]

METHODS AND RESULTS:
Extraction of the leaves of Chimarrhis turbinata has led to the isolation of turbinatine (1), a new corynanthean-type indole alkaloid, besides four known indole alkaloids, strictosidine, 5alpha-carboxystrictosidine, vallesiachotamine, and Isovallesiachotamine. The structural determination of 1 was based on 1D and 2D spectroscopic data.
CONCLUSIONS:
An evaluation of the DNA-damaging activities of the isolates was performed by means of a bioassay using mutant strains of Saccharomyces cerevisiae, which indicated these compounds were weakly active.
Isobavachin

Catalog No: CFN98400
CAS No: 31524-62-6
Price: $138/20mg
Taurocholic acid

Catalog No: CFN96646
CAS No: 81-24-3
Price: $ / mg
Dehydroglyasperin C

Catalog No: CFN96483
CAS No: 199331-35-6
Price: $ / mg
2''-O-Rhamnosylicariside II

Catalog No: CFN92551
CAS No: 135293-13-9
Price: $288/10mg
Oxoglaucine

Catalog No: CFN90508
CAS No: 5574-24-3
Price: $318/5mg
Lobetyolin

Catalog No: CFN99104
CAS No: 136085-37-5
Price: $168/20mg
Corynoxeine

Catalog No: CFN98154
CAS No: 630-94-4
Price: $148/20mg
Conduritol A

Catalog No: CFN98868
CAS No: 526-87-4
Price: $258/10mg
N-trans-caffeoyltyramine

Catalog No: CFN95265
CAS No: 103188-48-3
Price: $318/5mg
Kaempferol 3-neohesperidoside

Catalog No: CFN98415
CAS No: 32602-81-6
Price: $/mg
Tags: buy Isovallesiachotamine | Isovallesiachotamine supplier | purchase Isovallesiachotamine | Isovallesiachotamine cost | Isovallesiachotamine manufacturer | order Isovallesiachotamine | Isovallesiachotamine distributor